[HTML][HTML] Treatment of drug-induced liver injury

R Teschke - Biomedicines, 2022 - mdpi.com
Current pharmacotherapy options of drug-induced liver injury (DILI) remain under
discussion and are now evaluated in this analysis. Needless to say, the use of the offending …

[HTML][HTML] Molecular idiosyncratic toxicology of drugs in the human liver compared with animals: Basic considerations

R Teschke - International Journal of Molecular Sciences, 2023 - mdpi.com
Drug induced liver injury (DILI) occurs in patients exposed to drugs at recommended doses
that leads to idiosyncratic DILI and provides an excellent human model with well described …

Simultaneous detection of mitochondrial viscosity and peroxynitrite in livers from subjects with drug-induced fatty liver disease using a novel fluorescent probe

L Niu, Q Cao, T Zhang, Y Zhang, T Liang, J Wang - Talanta, 2023 - Elsevier
Drug-induced fatty liver disease (DIFLD) is a basic clinicopathological example of drug-
induced liver injury (DILI). Some drugs can inhibit β-oxidation in hepatocyte mitochondria …

Unraveling the link between insulin resistance and Non-alcoholic fatty liver disease (or metabolic dysfunction-associated steatotic liver disease): a Narrative Review

F Ziamanesh, M Mohammadi, S Ebrahimpour… - Journal of Diabetes & …, 2023 - Springer
Objective Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming a significant global
health concern, representing the leading cause of chronic liver disease and posing a …

[HTML][HTML] Targeting collagen homeostasis for the treatment of liver fibrosis: Opportunities and challenges

T Luangmonkong, W Parichatikanond… - Biochemical Pharmacology, 2023 - Elsevier
Liver fibrosis is an excessive production, aberrant deposition, and deficit degradation of
extracellular matrix (ECM). Patients with unresolved fibrosis ultimately undergo end-stage …

[HTML][HTML] Management of non-alcoholic fatty liver disease incidentally detected during other medical assessments

YY Lee, V Tee - Drugs in context, 2023 - ncbi.nlm.nih.gov
Elevated liver enzyme levels are a frequent incidental finding in primary care, and non-
alcoholic fatty liver disease is the main cause of incidental elevation of liver enzymes …

4-hydroxylonchocarpin and corylifol A: The potential hepatotoxic components of Psoralea corylifolia L

L Ouyang, Z Fan, Y He, L Tan, G Deng, Q He, Y He… - Toxicology letters, 2023 - Elsevier
Psoralea corylifolia L.(P. corylifolia) has attracted increasing attention because of its
potential hepatotoxicity. In this study, we used network analysis (toxic component and …

[HTML][HTML] Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats

S Menon, RA Al-Eisa, H Hamdi, L Lawrence… - Processes, 2023 - mdpi.com
In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was
evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen …

[HTML][HTML] Fatty liver change in Korean adults in a systematic social distancing system amid the COVID-19 pandemic: a multicenter analysis

JH Haam, YI Hur, YS Kim, KK Kim, JH Kang… - International Journal of …, 2022 - mdpi.com
In response to the COVID-19 pandemic, the Korean government implemented policies
including the systematic social distancing (SSD) system which started on 28 June 2020. The …

[HTML][HTML] Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and …

E López-Pascual, I Rienda, J Perez-Rojas… - International Journal of …, 2024 - mdpi.com
Drug induced fatty liver disease (DIFLD) is a form of drug-induced liver injury (DILI), which
can also be included in the more general metabolic dysfunction-associated steatotic liver …