The role of natural and semi-synthetic compounds in ovarian cancer: Updates on mechanisms of action, current trends and perspectives

MR Islam, MM Rahman, PS Dhar, FT Nowrin… - Molecules, 2023 - mdpi.com
Ovarian cancer represents a major health concern for the female population: there is no
obvious cause, it is frequently misdiagnosed, and it is characterized by a poor prognosis …

Exploring orphan GPCRs in neurodegenerative diseases

D Öz-Arslan, M Yavuz, B Kan - Frontiers in Pharmacology, 2024 - frontiersin.org
Neurodegenerative disorders represent a significant and growing health burden worldwide.
Unfortunately, limited therapeutic options are currently available despite ongoing efforts …

Identification of novel dual acting ligands targeting the adenosine A2A and serotonin 5-HT1A receptors

I Touati, M Abdalla, Y Boulaamane… - Journal of …, 2023 - Taylor & Francis
GPCRs are a family of transmembrane receptors that are profoundly linked to various
neurological disorders, among which is Parkinson's disease (PD). PD is the second most …

Potential of olfactory neuroepithelial cells as a model to study schizophrenia: A focus on GPCRs

ZA Sánchez‑Florentino… - International …, 2024 - spandidos-publications.com
Schizophrenia (SZ) is a multifactorial disorder characterized by volume reduction in gray
and white matter, oxidative stress, neuroinflammation, altered neurotransmission, as well as …

Neuropharmacological Potential of Ayurvedic Nanomedicines

P Kumar - Nanoarchitectonics for Brain Drug Delivery - taylorfrancis.com
Since a few decades ago, the burden of neurological illnesses has been increasing
exponentially, and it is currently the second biggest cause of mortality worldwide. The blood …