Vascular cognitive impairment (VCI) encompasses a range of cognitive deficits arising from
vascular pathology. The pathophysiological mechanisms underlying VCI remain …

Efficient signal transduction is important in maintaining the function of the nervous system
across tissues. An intact neurotransmission process can regulate energy balance through …

Neuronal death resulting from ischemic stroke is the primary cause of adult mortality and
disability, and effective neuroprotective agents for poststroke intervention are still lacking …

Diabetes exacerbates hemorrhagic transformation (HT) after stroke and worsens clinical
outcomes. Female patients with diabetes are at a greater risk of stroke and worsened …

OBJECTIVE: Cerebrovascular diseases (CVDs) remain an important public health issue due
to the increasing number of deaths worldwide. Changes in the synthesis and release of …

Stroke is a condition characterized by sudden deprivation of blood flow to a brain region and
defined by different post-injury phases, which involve various molecular and cellular …

Porphyran, a sulfated polysaccharide found in various species of marine red algae, has
been demonstrated to exhibit diverse bioactivities, including anti-inflammatory effects …

Acute ischemic stroke (AIS) is a challenging disease, which needs urgent comprehensive
management. Endovascular thrombectomy (EVT), alone or combined with iv thrombolysis, is …

Ischemia is a significant pathogenetic factor of stroke with very limited treatment options. The
objective of our research was to evaluate the protective properties of indole-3-carbinol (I3C) …

Transcription factor EB (TFEB) is an important endogenous defensive protein that responds
to ischemic stimuli. Acute ischemic stroke is a growing concern due to its high morbidity and …