Environmental toxicants and placental function

MS Bloom, M Varde, RB Newman - Best Practice & Research Clinical …, 2022 - Elsevier
The placenta is a temporary endocrine organ that facilitates gas, nutrient, and waste
exchange between maternal and fetal compartments, partially shielding the fetus from …

Perfluoroalkyl substance (PFAS) exposure and risk of nonalcoholic fatty liver disease in the elderly: Results from NHANES 2003–2014

Z Wu, T Ouyang, H Liu, L Cao, W Chen - Environmental Science and …, 2023 - Springer
This study aimed to investigate the association between perfluoroalkyl substance (PFAS)
exposure and the risk of nonalcoholic fatty liver disease (NAFLD) in the elderly. Our sample …

Gestational exposure to perfluoroalkyl substances is associated with placental DNA methylation and birth size

H Wang, W Li, J Yang, Y Wang, H Du, M Han… - Science of The Total …, 2023 - Elsevier
DNA methylation is one potential mechanism for the effects of gestational exposure to
perfluoroalkyl substances (PFASs) on fetal growth. We investigated 180 pregnant women …

[HTML][HTML] Biomonitoring equivalents for perfluorooctanoic acid (PFOA) for the interpretation of biomonitoring data

EL Tewfik, N Noisel, MA Verner - Environment International, 2023 - Elsevier
Background Perfluorooctanoic acid (PFOA) is detected in the blood of virtually all
biomonitoring study participants. Assessing health risks associated with blood PFOA levels …

Fluorotelomer ethoxylates cause developmental toxicity in mice

KL Steeves, J Hanrahan, NE Harvey… - Environmental …, 2024 - pubs.rsc.org
Poly-and perfluoroalkyl substances are a ubiquitous class of compounds which are
considered persistent organic pollutants. Many of these compounds are unregulated and …

Differential impact of perfluorooctanoic acid and fluorotelomer ethoxylates on placental metabolism in mice

H Adams, J Hanrahan, S Kiefte, T O'Brien, GV Mercer… - Chemosphere, 2024 - Elsevier
Poly-and perfluoroalkyl substances (PFAS) are a group of compounds with uses in industry
and many consumer products. Concerns about the potential health effects of these …

[HTML][HTML] Placental inflammatory injury induced by chlorinated polyfluorinated ether sulfonate (F-53B) through NLRP3 inflammasome activation

C Chu, H Ran, Y Zhou, K Zhao, YT Zhang… - Ecotoxicology and …, 2024 - Elsevier
Chlorinated polyfluorinated ether sulfonate, commercially known as F-53B, has been
associated with adverse birth outcomes. However, the reproductive toxicology of F-53B on …

Male infertility and Perfluoroalkyl and poly-fluoroalkyl substances: Evidence for alterations in phosphorylation of proteins and fertility-related functional attributes in bull …

A Kumaresan, P Yadav, MK Sinha, P Nag… - Biology of …, 2024 - academic.oup.com
Background Perfluoroalkyl and poly-fluoroalkyl substances (PFAS) are pervasive
environmental pollutants and emerging risk factors for reproductive health. Although …

PFOS-induced Sertoli cell injury through c-Jun N-terminal kinase (JNK)-a study by RNA-Seq

S Gao, Z Chen, X Wu, L Wang, T Bu… - … of Physiology-Cell …, 2024 - journals.physiology.org
Per-and polyfluoroalkyl substances (PFAS) are a family of" forever chemicals" including
PFOS (perfluorooctane sulfonate). These toxic chemicals do not break down in the …

Associations of perfluoroalkyl substances with metabolic-associated fatty liver disease and non-alcoholic fatty liver disease: NHANES 2017–2018

Y Zhang, M Zhang, S Jiang, H Hu, X Wang, F Yu… - Cancer Causes & …, 2024 - Springer
Objectives This study investigated the potential effects of perfluoroalkyl substance (PFAS) in
serum on MAFLD, NAFLD, and liver fibrosis. Methods Our sample included 696 participants …