Prostaglandin E2 and cancer: insight into tumor progression and immunity

F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Cytokine‐and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

AA Bhat, S Nisar, M Singh, B Ashraf… - Cancer …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

Curcumin and colorectal cancer: from basic to clinical evidences

M Pricci, B Girardi, F Giorgio, G Losurdo… - International journal of …, 2020 - mdpi.com
Curcumin diffuses through cell membranes into the endoplasmic reticulum, mitochondria,
and nucleus, where it exerts actions, as an antioxidant property. Therefore, its use has been …

[HTML][HTML] Colorectal cancer carcinogenesis: a review of mechanisms

K Tariq, K Ghias - Cancer biology & medicine, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …

Long non‐coding RNA cox‐2 prevents immune evasion and metastasis of hepatocellular carcinoma by altering M1/M2 macrophage polarization

Y Ye, Y Xu, YU Lai, W He, Y Li, R Wang… - Journal of Cellular …, 2018 - Wiley Online Library
Macrophages have been shown to demonstrate a high level of plasticity, with the ability to
undergo dynamic transition between M1 and M2 polarized phenotypes. We investigate long …

[HTML][HTML] The role of cyclooxygenase-2 in colorectal cancer

J Sheng, H Sun, FB Yu, B Li, Y Zhang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Colorectal cancer is the third common cancer in this world, accounting for more than 1
million cases each year. However, detailed etiology and mechanism of colorectal cancer …

Mechanism of apoptosis induced by curcumin in colorectal cancer

NI Ismail, I Othman, F Abas, N H. Lajis… - International journal of …, 2019 - mdpi.com
Colorectal cancer (CRC) is among the top three cancer with higher incident and mortality
rate worldwide. It is estimated that about over than 1.1 million of death and 2.2 million new …

Luteolin suppresses the JAK/STAT pathway in a cellular model of intestinal inflammation

C Nunes, L Almeida, RM Barbosa, J Laranjinha - Food & function, 2017 - pubs.rsc.org
Current treatment strategies for inflammatory bowel diseases (IBDs) are associated with a
lower efficacy and with several side effects that strongly affect the quality of life of IBD …

Synergistic platinum (II) prodrug nanoparticles for enhanced breast cancer therapy

CX Yang, L Xing, X Chang, TJ Zhou, YY Bi… - Molecular …, 2020 - ACS Publications
Chemotherapy still accounts for a large proportion of the treatments of tumors, but the drug
resistance and side effects caused by long-term chemotherapy should not be …

Looking at NSAIDs from a historical perspective and their current status in drug repurposing for cancer treatment and prevention

A Ozleyen, YB Yilmaz, S Donmez, HN Atalay… - Journal of Cancer …, 2023 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed
drug classes with wide therapeutic applications over the centuries. Starting from the use of …