[HTML][HTML] Expression profile of NF-κB regulated genes in sporadic colorectal cancer patients
BA González‑Quezada… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is the fourth leading worldwide cause of cancer‑associated
mortalities. Nuclear factor‑κB (NF‑κB) is a transcriptional regulator of multiple genes …
mortalities. Nuclear factor‑κB (NF‑κB) is a transcriptional regulator of multiple genes …
β‐Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC
E Fredericks, G Dealtry, S Roux - Canadian Journal of …, 2018 - Wiley Online Library
Background. The wnt/APC/β‐catenin pathway is a critical initiator in colorectal
carcinogenesis in both hereditary and sporadic colorectal cancer (CRC). The progression of …
carcinogenesis in both hereditary and sporadic colorectal cancer (CRC). The progression of …
[HTML][HTML] miR-26b mimic inhibits glioma proliferation in vitro and in vivo suppressing COX-2 expression
ZG Chen, CY Zheng, WQ Cai, DW Li, FY Ye… - Oncology …, 2019 - ncbi.nlm.nih.gov
Glioma is the most common malignant tumor of the nervous system. Studies have shown the
microRNA-26b (miR-26b)/cyclooxygenase-2 (COX-2) axis in the development and …
microRNA-26b (miR-26b)/cyclooxygenase-2 (COX-2) axis in the development and …
Exenatide suppresses 1, 2-dimethylhydrazine-induced colon cancer in diabetic mice: Effect on tumor angiogenesis and cell proliferation
MK Tawfik, MI Mohamed - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Colon cancer is the third leading cause of cancer mortality worldwide, which results from
interactions of different factors. It is frequently a pathological consequence of persistent …
interactions of different factors. It is frequently a pathological consequence of persistent …
[HTML][HTML] Colorectal carcinoma, cyclooxygenases, and Cox inhibitors
V Ganduri, K Rajasekaran, S Duraiyarasan… - Cureus, 2022 - ncbi.nlm.nih.gov
Colorectal carcinoma (CRC) is the most common of gastrointestinal cancers, the majority
presenting with sporadic occurrence compared to the less frequently inherited syndromes …
presenting with sporadic occurrence compared to the less frequently inherited syndromes …
Tissue specific promoters in colorectal cancer
AR Rama, A Aguilera, C Melguizo, O Caba… - Disease …, 2015 - Wiley Online Library
Colorectal carcinoma is the third most prevalent cancer in the world. In the most advanced
stages, the use of chemotherapy induces a poor response and is usually accompanied by …
stages, the use of chemotherapy induces a poor response and is usually accompanied by …
Variances in the level of COX-2 and iNOS in different grades of endometrial cancer
M Oplawski, K Dziobek, N Zmarzły… - Current …, 2020 - ingentaconnect.com
Background: Many experimental studies have demonstrated the importance of COX-2 in the
tumor angiogenesis. Inducible iNOS is responsible for a high and stable level of nitric oxide …
tumor angiogenesis. Inducible iNOS is responsible for a high and stable level of nitric oxide …
[HTML][HTML] mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency
H Li, F Jin, K Jiang, S Ji, L Wang, Z Ni, X Chen, Z Hu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Tuberous sclerosis complex (TSC), caused by loss-of-function mutations in the TSC1 or
TSC2 gene, is characterized by benign tumor formation in multiple organs. Hyperactivation …
TSC2 gene, is characterized by benign tumor formation in multiple organs. Hyperactivation …
Inhibition of nuclear factor-kappaB, cyclooxygenase-2, and metalloproteinase-9 expression by flavanols from evening primrose (Oenothera paradoxa) in human colon …
The present study examines the chemical composition of an evening primrose flavanol
preparation (EPFP) and its chemopreventive activity in colon cancer SW-480 cells. EPFP …
preparation (EPFP) and its chemopreventive activity in colon cancer SW-480 cells. EPFP …
Discovery, synthesis, and anti-cancer evaluation of 10-Pterostilbene methylamine hydrochloride derivatives as potential COX-2 and Topo I dual inhibitors
Y Huang, S Wang, S Huang, W Pan, XJ Luo… - Journal of Molecular …, 2024 - Elsevier
Abstract A series of (E)-N-benzyl-1-(2, 4-dimethoxy-6-(4 methoxystyryl) phenyl)
methanamine (DMPM) derivatives (D1-D25) were successfully synthesized in the form of …
methanamine (DMPM) derivatives (D1-D25) were successfully synthesized in the form of …