Insulin-like growth factor 2 mRNA-binding proteins (IMPs, IGF2BPs) act in mRNA transport
and translational control but are oncofetal tumor marker proteins. The IMP protein family …

RNAs exhibit a plethora of functions far beyond transmitting genetic information. Often, RNA
functions are entailed in their structure, be it as a regulatory switch, protein binding site, or …

The nucleocapsid protein (N) of SARS-CoV-2 plays a pivotal role during the viral life cycle. It
is involved in RNA transcription and accounts for packaging of the large genome into virus …

Control of posttranscriptional mRNA decay is a crucial determinant of cell homeostasis and
differentiation. mRNA lifetime is governed by cis-regulatory elements in their 3 …

Dynamic changes in gene expression are key factors in the development and activation of
immune cells. RNA metabolism is one of the critical steps for the control of gene expression …

Alzheimer's disease (AD) is a heterogeneous degenerative disorder of the brain that is on
the rise worldwide. One of the critical processes that might be disturbed in AD is gene …

The RNA-binding proteins Roquin-1/2 and Regnase-1 exert essential regulation by
controlling pro-inflammatory mRNA expression to prevent autoimmune disease. More …

MicroRNAs (miRNAs) have emerged as critical posttranscriptional regulators of the immune
system, including function and development of regulatory T (Treg) cells. Although this critical …

In recent years, it has become clear that RNA molecules are involved in almost all vital
cellular processes and pathogenesis of human disorders. The functional diversity of RNA …

Zinc finger (ZnF) domains appear in a pool of structural contexts and despite their small size
achieve varying target specificities, covering single-stranded and double-stranded DNA and …