Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Recent advances and perspectives of metabolomics-based investigations in Parkinson's disease

Y Shao, W Le - Molecular neurodegeneration, 2019 - Springer
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease of the
central nervous system (CNS), which affects mostly older adults. In recent years, the …

Phytotoxicity of microplastics to the floating plant Spirodela polyrhiza (L.): Plant functional traits and metabolomics

Y Wang, J Bai, L Wen, W Wang, L Zhang, Z Liu… - Environmental …, 2023 - Elsevier
Freshwater ecosystems are gradually becoming sinks for terrestrial microplastics (MPs),
posing a potential ecological risk. Although the effects of MPs on plankton and aquatic …

Translational metabolomics: current challenges and future opportunities

FR Pinu, SA Goldansaz, J Jaine - Metabolites, 2019 - mdpi.com
Metabolomics is one of the latest omics technologies that has been applied successfully in
many areas of life sciences. Despite being relatively new, a plethora of publications over the …

Plants metabolome study: Emerging tools and techniques

MK Patel, S Pandey, M Kumar, MI Haque, S Pal… - Plants, 2021 - mdpi.com
Metabolomics is now considered a wide-ranging, sensitive and practical approach to
acquire useful information on the composition of a metabolite pool present in any organism …

Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

Metabolomics identifies serum and exosomes metabolite markers of pancreatic cancer

L Tao, J Zhou, C Yuan, L Zhang, D Li, D Si, D Xiu… - Metabolomics, 2019 - Springer
Introduction Pancreatic cancer (PC) is one of the most aggressive malignancies, and it's
difficult to diagnosis PC at an early stage, which leads to the poor prognosis of PC …

Metabolomics-based engineering for biofuel and bio-based chemical production in microalgae and cyanobacteria: A review

Y Kato, K Inabe, R Hidese, A Kondo… - Bioresource Technology, 2022 - Elsevier
Metabolomics, an essential tool in modern synthetic biology based on the design-build-test-
learn platform, is useful for obtaining a detailed understanding of cellular metabolic …

[HTML][HTML] Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and …

SU Vorrink, S Ullah, S Schmidt, J Nandania… - The FASEB …, 2017 - ncbi.nlm.nih.gov
Adverse reactions or lack of response to medications are important concerns for drug
development programs. However, faithful predictions of drug metabolism and toxicity are …

Data acquisition workflows in liquid chromatography coupled to high resolution mass spectrometry-based metabolomics: Where do we stand?

F Fenaille, PB Saint-Hilaire, K Rousseau… - … of Chromatography a, 2017 - Elsevier
Typical mass spectrometry (MS) based untargeted metabolomics protocols are tedious as
well as time-and sample-consuming. In particular, they often rely on “full-scan-only” …