Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Inflammation is emerging as one of the hallmarks of cancer, yet its role in most tumors
remains unclear. Whereas a minority of solid tumors are associated with overt inflammation …

Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and
inflammation in patients with arthritic conditions, and also acutely as analgesics by many …

Although colorectal cancer (CRC) screening has reduced the incidence of and mortality from
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …

Colorectal cancer has been strongly associated with a Western lifestyle. In the past several
decades, much has been learned about the dietary, lifestyle, and medication risk factors for …

Human platelets arise as subcellular fragments of megakaryocytes in bone marrow. The
physiologic demand, presence of disease such as cancer, or drug effects can regulate the …

Colorectal cancer (CRC) is a heterogeneous disease, including at least three major forms:
hereditary, sporadic and colitis-associated CRC. A large body of evidence indicates that …

The number of colorectal cancer (CRC) patients is increasing worldwide. Accumulating
evidence has shown that the tumor microenvironment (TME), including macrophages …

Recent scientific advances have contributed much to the dissection of the complex
molecular and cellular pathways involved in the connection between cancer and …

Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs
in an undetectable and asymptomatic state for many years. These lesions do not progress in …