Phosphorylation impacts Cu (II) binding by ATCUN motifs

T Fraczyk - Inorganic chemistry, 2021 - ACS Publications
ATCUN (amino terminal Cu (II) and Ni (II) binding) motifs chelate Cu (II) ions strongly.
However, the impact of the phosphorylation of neighboring residues on such complexation …

Copper (II), Nickel (II) and Zinc (II) Complexes of Peptide Fragments of Tau Protein

Z Kastal, A Balabán, S Vida, C Kállay, L Nagy… - Molecules, 2024 - mdpi.com
Copper (II), nickel (II) and zinc (II) complexes of various peptide fragments of tau protein
were studied by potentiometric and spectroscopic techniques. All peptides contained one …

Ni (II) ions may target the entire melatonin biosynthesis pathway—a plausible mechanism of nickel toxicity

NE Wezynfeld, AM Bonna, D Płonka, W Bal, T Frączyk - Molecules, 2022 - mdpi.com
Nickel is toxic to humans. Its compounds are carcinogenic. Furthermore, nickel allergy is a
severe health problem that affects approximately 10–20% of humans. The mechanism by …

Peptide bond cleavage in the presence of Ni-containing particles

NE Wezynfeld, T Frączyk, A Bonna, W Bal - Metallomics, 2020 - academic.oup.com
NiO nanoparticles and non-stoichiometric black NiO were shown to be effective sources of
Ni2+ ions causing sequence-selective peptide bond hydrolysis. NiO nanoparticles were as …