The paper forms part of a series of papers outlining the theoretical framework for a new
model of uncertainty distress (this paper), treatment implications arising from the model, and …

Intolerance of uncertainty (IU), the tendency to find uncertainty aversive, is an important
transdiagnostic dimension in mental health disorders. Over the last decade, there has been …

Uncertainty and emotion are an inevitable part of everyday life and play a vital role in mental
health. Yet, our understanding of how uncertainty and emotion interact is limited. Here, an …

Neuroimaging research has identified a network of brain regions that is consistently more
engaged when people think about the minds of other people than when they engage in …

Prior studies show that individuals with alcohol use disorder exhibit exaggerated behavioral
and brain reactivity to uncertain threats (U-threat). It is posited this brain-based factor …

Abstract Design is a ubiquitous, complex, and open-ended creation behaviour that triggers
creativity. The brain dynamics underlying design is unclear, since a design process consists …

Extinction-resistant threat is considered to be a central feature of pathological anxiety.
Reduced threat extinction is observed in individuals with high intolerance of uncertainty (IU) …

Heightened responding to uncertain threat is considered a hallmark of anxiety disorder
pathology. We sought to determine whether individual differences in self-reported …

Accurately estimating safety is critical to pursuing nondefensive survival behaviors.
However, little attention has been paid to how the human brain computes safety. We …

Heightened physiological responses to uncertainty are a common hallmark of anxiety
disorders. Many separate studies have examined the relationship between individual …