Cell death in pancreatic cancer: from pathogenesis to therapy
Pancreatic cancer is a devastating gastrointestinal cancer characterized by late diagnosis,
limited treatment success and dismal prognosis. Exocrine tumours account for 95% of …
limited treatment success and dismal prognosis. Exocrine tumours account for 95% of …
Lipid metabolism in cancer progression and therapeutic strategies
Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
Dysregulated lipid metabolism represents an important metabolic alteration in cancer. Fatty
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …
acids, cholesterol, and phospholipid are the three most prevalent lipids that act as energy …
[HTML][HTML] The diversity and breadth of cancer cell fatty acid metabolism
Tumor cellular metabolism exhibits distinguishing features that collectively enhance
biomass synthesis while maintaining redox balance and cellular homeostasis. These …
biomass synthesis while maintaining redox balance and cellular homeostasis. These …
[HTML][HTML] FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism
C Zhang, Y Liao, P Liu, Q Du, Y Liang, S Ooi, S Qin… - Theranostics, 2020 - ncbi.nlm.nih.gov
Patients with cervical cancer (CCa) with lymph node metastasis (LNM) have an extremely
poor prognosis. Elucidation of the molecular mechanisms underlying LNM may provide …
poor prognosis. Elucidation of the molecular mechanisms underlying LNM may provide …
[HTML][HTML] Reprogramming of lipid metabolism in lung cancer: An overview with focus on EGFR-Mutated non-small cell lung cancer
K Eltayeb, S La Monica, M Tiseo, R Alfieri, C Fumarola - Cells, 2022 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide. Most of lung cancer cases are
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
[HTML][HTML] Aberrations in lipid expression and metabolism in psoriasis
J Nowowiejska, A Baran, I Flisiak - International journal of molecular …, 2021 - mdpi.com
Psoriasis (PSO) is a common skin disease that affects about 1%–3% of the general
population. It is a great medical, social and economic burden since PSO is associated with …
population. It is a great medical, social and economic burden since PSO is associated with …
[HTML][HTML] FABP4 in obesity-associated carcinogenesis: Novel insights into mechanisms and therapeutic implications
S Liu, D Wu, Z Fan, J Yang, Y Li, Y Meng… - Frontiers in Molecular …, 2022 - frontiersin.org
The increasing prevalence of obesity worldwide is associated with an increased risk of
various diseases, including multiple metabolic diseases, cardiovascular diseases, and …
various diseases, including multiple metabolic diseases, cardiovascular diseases, and …
Pathogenesis of alcohol-associated liver disease
Excessive alcohol consumption is a global healthcare problem with enormous social,
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …
[HTML][HTML] FABP5 as a novel molecular target in prostate cancer
SE O'Sullivan, M Kaczocha - Drug Discovery Today, 2020 - Elsevier
Highlights•Fatty acid binding protein 5 (FABP5) is upregulated in many cancers, particularly
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …
prostate cancer (PC).•FABP5 facilitates the delivery of fatty acids to peroxisome proliferator …
[HTML][HTML] Resveratrol inhibits proliferation and induces autophagy by blocking SREBP1 expression in oral cancer cells
M Fukuda, Y Ogasawara, H Hayashi, K Inoue… - Molecules, 2022 - mdpi.com
Resveratrol is a polyphenolic antioxidant found in grapes, red wine, and peanuts and has
been reported to have anti-neoplastic effects on various cancer types. However, the exact …
been reported to have anti-neoplastic effects on various cancer types. However, the exact …