Various factors could damage the structure and integrity of skin to cause wounds.
Nonhealing or chronic wounds seriously affect the well-being of patients and bring heavy …

Wound healing is a common physiological process which consists of a sequence of
molecular and cellular events that occur following the onset of a tissue lesion in order to …

Abstract The Human Reference Atlas (HRA) aims to map all of the cells of the human body
to advance biomedical research and clinical practice. This Perspective presents …

The Hanahan and Weinberg “hallmarks of cancer” papers provide a useful structure for
considering the various mechanisms driving cancer progression, and the same might be …

In the last decade, the advent of 3D printing for tissue engineering and regenerative
medicine has engendered great interest for those involved in skin repair and regeneration …

Chronic skin wounds are the leading cause of nontraumatic foot amputations worldwide and
present a significant risk of morbidity and mortality due to the lack of efficient therapies. The …

Stem cells support lifelong maintenance of adult organs, but their specific roles during injury
are poorly understood. Here we demonstrate that Lgr6 marks a regionally restricted …

The human skin is a highly specialized organ for receiving sensory information but also to
preserve the body's homeostasis. These functions are mediated by cutaneous small nerve …

Diabetic peripheral neuropathies (DPN) are a heterogeneous group of disorders caused by
neuronal dysfunction in patients with diabetes. They have differing clinical courses …

The nervous and immune systems are classically studied as two separate entities. However,
their interactions are crucial for maintaining barrier functions at tissues constantly exposed to …