[HTML][HTML] Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

X Yuan, H Wu, N Han, H Xu, Q Chu, S Yu… - Journal of hematology & …, 2014 - Springer
Through epithelial-mesenchymal transition (EMT), cancer cells acquire enhanced ability of
migration and invasion, stem cell like characteristics and therapeutic resistance. Notch …

[HTML][HTML] Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance

Y Ren, X Mao, H Xu, Q Dang, S Weng, Y Zhang… - Cellular and Molecular …, 2023 - Springer
Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

[HTML][HTML] Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell …

L Wang, X Tong, Z Zhou, S Wang, Z Lei, T Zhang, Z Liu… - Molecular cancer, 2018 - Springer
Background TGF-β promotes tumor invasion and metastasis through inducing epithelial-
mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC). Circular RNAs …

Ginkgolic acid inhibits invasion and migration and tgf‐β‐induced emt of lung cancer cells through pi3k/akt/mtor inactivation

SH Baek, JH Ko, JH Lee, C Kim, H Lee… - Journal of cellular …, 2017 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT) is a critical cellular phenomenon regulating
tumor metastases. In the present study, we investigated whether ginkgolic acid can affect …

Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis

H Wang, H Zhang, L Tang, H Chen, C Wu, M Zhao… - Toxicology, 2013 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a cellular process during which epithelial
polarized cells become motile mesenchymal-appearing cells, which in turn promotes …

[HTML][HTML] Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant

W Van Roosmalen, SE Le Dévédec… - The Journal of …, 2015 - Am Soc Clin Investig
Tumor cell migration is a key process for cancer cell dissemination and metastasis that is
controlled by signal-mediated cytoskeletal and cell matrix adhesion remodeling. Using a …

[HTML][HTML] miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells

J Li, Y Wang, J Luo, Z Fu, J Ying, Y Yu, W Yu - FEBS letters, 2012 - Elsevier
Recent studies have implied that miRNAs act as crucial modulators for epithelial-to-
mesenchymal transition (EMT). We found that miR-134 expression correlated with invasive …

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α …

G Li, Y Zhang, Y Qian, H Zhang, S Guo… - Molecular …, 2013 - Elsevier
Both hypoxia and interleukin-17A (IL-17A) promote the migration and invasion of fibroblast-
like synoviocytes (FLSs), which are critical for the pathogenesis of rheumatoid arthritis (RA) …

[HTML][HTML] Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

S Xi, H Xu, J Shan, Y Tao, JA Hong… - The Journal of …, 2013 - Am Soc Clin Investig
MicroRNAs are critical mediators of stem cell pluripotency, differentiation, and malignancy.
Limited information exists regarding microRNA alterations that facilitate initiation and …

Resveratrol reduces gentamicin-induced EMT in the kidney via inhibition of reactive oxygen species and involving TGF-β/Smad pathway

ON Beshay, MG Ewees, MS Abdel-Bakky, SMNA Hafez… - Life Sciences, 2020 - Elsevier
Aims Gentamicin (GEN) is one of the most valuable aminoglycoside antibiotics utilized
against life-threatening bacterial infections. Unfortunately, GEN-induced nephrotoxicity …