[HTML][HTML] Exploring the latest trends in chemistry, structure, coordination, and diverse applications of 1-acyl-3-substituted thioureas: a comprehensive review
Acyl thioureas represent a privileged moiety with vast potential applicability across diverse
fields, making them the subject of extensive research efforts. The inherent flexibility of …
fields, making them the subject of extensive research efforts. The inherent flexibility of …
Virtual screening, molecular docking, and dynamic simulations revealed TGF-β1 potential inhibitors to curtail cervical cancer progression
Cervical cancer is one of the main causes of cancer death in women globally, and its
epidemiology is similar to that of a low-infectious venereal illness. Many sexual partners and …
epidemiology is similar to that of a low-infectious venereal illness. Many sexual partners and …
Mechanistic insights and therapeutic implications of novel pyrazoline derivatives on antioxidant and enzymatic inhibitory activities
One of the major features of medicinal chemistry, is the synthesis of novel compounds, and
the assessment of their biological activities for potential therapeutic applications. As a …
the assessment of their biological activities for potential therapeutic applications. As a …
4, 5-difluoro-2-((m-tolylimino) methyl) phenol: Investigations on a synthesized Schiff base with in silico medicinal approaches and DFT studies
S Şahin - Journal of Molecular Structure, 2024 - Elsevier
A new Schiff base structure, 4, 5-difluoro-2-((m-tolylimino) methyl) phenol was synthesized
and characterized. The DFT studies were performed at the B3LYP level with the 6–311++ G …
and characterized. The DFT studies were performed at the B3LYP level with the 6–311++ G …
Novel thiourea derivatives against Mycobacterium tuberculosis: synthesis, characterization and molecular docking studies
Abstract N-((2-chloropyridin-3-yl) carbamothioyl) thiophene-2-carboxamide (HL1), N-((6-
methylpyridin-2-yl) carbamothioyl) thiophene-2-carboxamide (HL2), N-(allylcarbamothioyl) …
methylpyridin-2-yl) carbamothioyl) thiophene-2-carboxamide (HL2), N-(allylcarbamothioyl) …
Synthesis, Structural Elucidation, In Silico and In Vitro Studies of New Class of Methylenedioxyphenyl-Based Amide Derivatives as Potential Myeloperoxidase …
R Rajan, S Karthikeyan, R Desikan - ACS omega, 2024 - ACS Publications
Novel methylenedioxyphenyl-based amides, especially N-(4-methoxybenzyl)-6-nitrobenzo-
[1, 3]-dioxole-5-carboxamide (MDC) and N-(3-acetylphenyl)-6-nitrobenzo-[1, 3]-dioxole-5 …
[1, 3]-dioxole-5-carboxamide (MDC) and N-(3-acetylphenyl)-6-nitrobenzo-[1, 3]-dioxole-5 …
Homology Modeling, Screening, and Identification of Potential FOXO6 Inhibitors Curtail Gastric Cancer Progression: an In Silico Drug Repurposing Approach
SM Poleboyina, PK Poleboyina, SC Pawar… - Applied Biochemistry …, 2023 - Springer
Gastric cancer is the world's second leading cause of cancer-related fatalities, with the
epidemiology changing over the previous several decades. FOXOs are the O subfamily of …
epidemiology changing over the previous several decades. FOXOs are the O subfamily of …
New 1-Arylmethyl-3-Benzoyl/Cyclopropanoyl Thioureas as inhibitors of AGS cell line migration: Synthesis, biological evaluation and molecular dynamics
M Sagha, KA Mortazavi, JA Shiran, AA Tehrani… - Journal of Molecular …, 2024 - Elsevier
Human gastric adenocarcinoma is one of the common malignant tumors that is highly
responsible for cancer-associated mortality. Besides available treatment strategies, patients …
responsible for cancer-associated mortality. Besides available treatment strategies, patients …