Historical perspective on effects and treatment of sulfur mustard injuries

JS Graham, BA Schoneboom - Chemico-biological interactions, 2013 - Elsevier
Abstract Sulfur mustard (2, 2′-dichlorodiethyl sulfide; SM) is a potent vesicating chemical
warfare agent that poses a continuing threat to both military and civilian populations …

Sea-dumped chemical weapons: environmental risk, occupational hazard

MI Greenberg, KJ Sexton, D Vearrier - Clinical Toxicology, 2016 - Taylor & Francis
Introduction: Chemical weapons dumped into the ocean for disposal in the twentieth century
pose a continuing environmental and human health risk. Objective: In this review we discuss …

Acute intensive care unit management of mustard gas victims: the Turkish experience

E Kilic, M Ortatatli, S Sezigen, RK Eyison… - Cutaneous and ocular …, 2018 - Taylor & Francis
Purpose: Sulphur mustard (SM) is an highly toxic and vesicant chemical weapon that was
used in various military conflicts several times in the history. The severity of ocular, dermal …

[HTML][HTML] Four sulfur mustard exposure cases: overall analysis of four types of biomarkers in clinical samples provides positive implication for early diagnosis and …

H Xu, Z Nie, Y Zhang, C Li, L Yue, W Yang, J Chen… - Toxicology reports, 2014 - Elsevier
In one event, Chinese male individuals accidentally exposed to unknown chemicals and
emerged erythema or blisters on contacted organism derma, then hospitalized. To identify …

Acute and chronic effects of sulfur mustard on the skin: a comprehensive review

M Ghanei, Z Poursaleh, AA Harandi… - … and ocular toxicology, 2010 - Taylor & Francis
Sulfur mustard (2, 2-dichlorodiethyl sulfide, SM) is one of the vesicant classes of chemical
warfare agents that causes blistering in the skin and mucous membranes, where it can have …

The limitations of diazepam as a treatment for nerve agent–induced seizures and neuropathology in rats: comparison with UBP302

JP Apland, V Aroniadou-Anderjaska… - … of Pharmacology and …, 2014 - ASPET
Exposure to nerve agents induces prolonged status epilepticus (SE), causing brain damage
or death. Diazepam (DZP) is the current US Food and Drug Administration–approved drug …

Simplified method for quantifying sulfur mustard adducts to blood proteins by ultrahigh pressure liquid chromatography–isotope dilution tandem mass spectrometry

BG Pantazides, BS Crow, JW Garton… - Chemical research in …, 2015 - ACS Publications
Sulfur mustard binds to reactive cysteine residues, forming a stable sulfur-
hydroxyethylthioethyl [S-HETE] adduct that can be used as a long-term biomarker of sulfur …

Analysis of urinary metabolites of sulfur mustard in two individuals after accidental exposure

JR Barr, CL Pierce, JR Smith… - Journal of analytical …, 2008 - academic.oup.com
In July 2004, two individuals developed blisters after the destruction of a WWI-era munition.
To determine the causative agent, urine samples were collected from both the highly …

Retrospective detection of sulfur mustard exposure by mass spectrometric analysis of adducts to albumin and hemoglobin: an in vivo study

D Noort, A Fidder… - Journal of analytical …, 2008 - academic.oup.com
The persistence in rats of sulfur mustard adducts to albumin and hemoglobin was studied in
vivo after exposure (intravenously; 0.3 mg/kg; approximately 0.1 LD50) of rats to sulfur …

A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure

T Zubel, S Hochgesand, H John, D Steinritz… - Archives of …, 2019 - Springer
Despite its worldwide ban, the warfare agent sulfur mustard (SM) still represents a realistic
threat, due to potential release in terroristic attacks and asymmetric conflicts. Therefore, the …