The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …

For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …

Over the last decade several novel surgical treatment options and devices for glaucoma
have been developed. All these developments aim to cause as little trauma as possible to …

Despite high metabolic activity, the retina and optic nerve head lack traditional lymphatic
drainage. We here identified an ocular glymphatic clearance route for fluid and wastes via …

The trabecular meshwork regulates aqueous humour outflow from the anterior chamber of
the eye. It does this by establishing a tunable outflow resistance, defined by the interplay …

Glaucoma is a leading cause of irreversible blindness worldwide. Elevated intraocular
pressure (IOP) is considered to be a predominant risk factor for primary open angle …

Polyunsaturated fatty acids (PUFA) are known to have numerous beneficial effects, owing to
their anti-inflammatory and antioxidant properties. From a metabolic standpoint, the …

Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness
worldwide. Increasing evidence suggests oxidative damage and immune response defects …

Glaucoma is a degenerative disease of the eye. Both the anterior and posterior segments of
the eye are affected, extensive damage being detectable in the trabecular meshwork and …

Saffron (Crocus sativus L.) and its main constituents, ie, crocin and crocetin, are natural
carotenoid compounds, which have been reported to possess a wide spectrum of properties …