[HTML][HTML] Cytokine storm—definition, causes, and implications
D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …
[HTML][HTML] Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis
Background Septic shock is the most severe form of sepsis, in which profound underlying
abnormalities in circulatory and cellular/metabolic parameters lead to substantially …
abnormalities in circulatory and cellular/metabolic parameters lead to substantially …
Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of …
WC Meijers, A Bayes‐Genis, A Mebazaa… - European journal of …, 2021 - Wiley Online Library
New biomarkers are being evaluated for their ability to advance the management of patients
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …
with heart failure. Despite a large pool of interesting candidate biomarkers, besides …
[HTML][HTML] Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review
C Aldecoa, JV Llau, X Nuvials, A Artigas - Annals of Intensive Care, 2020 - Springer
The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans,
secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such …
secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such …
[HTML][HTML] Head-to-head comparison of qSOFA and SIRS criteria in predicting the mortality of infected patients in the emergency department: a meta-analysis
J Jiang, J Yang, J Mei, Y Jin, Y Lu - Scandinavian journal of trauma …, 2018 - Springer
Background Recently, the concept of sepsis was redefined by an international task force.
This international task force of experts recommended using the quick Sequential Organ …
This international task force of experts recommended using the quick Sequential Organ …
[HTML][HTML] Biomarkers as prognostic predictors and therapeutic guide in critically ill patients: clinical evidence
R Méndez Hernández, F Ramasco Rueda - Journal of Personalized …, 2023 - mdpi.com
A biomarker is a molecule that can be measured in a biological sample in an objective,
systematic, and precise way, whose levels indicate whether a process is normal or …
systematic, and precise way, whose levels indicate whether a process is normal or …
[HTML][HTML] Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease)
JF Bermejo-Martin, M Martín-Fernandez… - Journal of clinical …, 2018 - mdpi.com
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,
increasing vascular permeability, promoting activation of the coagulation cascade, tissue …
increasing vascular permeability, promoting activation of the coagulation cascade, tissue …
[HTML][HTML] The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and …
Background There is a lack of validated tools to assess potential disease progression and
hospitalisation decisions in patients presenting to the emergency department (ED) with a …
hospitalisation decisions in patients presenting to the emergency department (ED) with a …
[HTML][HTML] Electroanalytical point-of-care detection of gold standard and emerging cardiac biomarkers for stratification and monitoring in intensive care medicine-a …
RD Crapnell, NC Dempsey, E Sigley, A Tridente… - Microchimica Acta, 2022 - Springer
Determination of specific cardiac biomarkers (CBs) during the diagnosis and management
of adverse cardiovascular events such as acute myocardial infarction (AMI) has become …
of adverse cardiovascular events such as acute myocardial infarction (AMI) has become …
[HTML][HTML] An update on sepsis biomarkers
MH Kim, JH Choi - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
Sepsis is a dysregulated systemic reaction to a common infection, that can cause life-
threatening organ dysfunction. Over the last decade, the mortality rate of patients with sepsis …
threatening organ dysfunction. Over the last decade, the mortality rate of patients with sepsis …