[HTML][HTML] Let's get physical: flavivirus-host protein–protein interactions in replication and pathogenesis

AT Fishburn, OH Pham, MW Kenaston… - Frontiers in …, 2022 - frontiersin.org
Flaviviruses comprise a genus of viruses that pose a significant burden on human health
worldwide. Transmission by both mosquito and tick vectors, and broad host tropism …

[HTML][HTML] Zika virus neuropathogenesis: The different brain cells, host factors and mechanisms involved

TV Komarasamy, NAA Adnan, W James… - Frontiers in …, 2022 - frontiersin.org
Zika virus (ZIKV), despite being discovered six decades earlier, became a major health
concern only after an epidemic in French Polynesia and an increase in the number of …

[HTML][HTML] Hide and seek: the interplay between Zika virus and the host immune response

LJ Lee, TV Komarasamy, NAA Adnan… - Frontiers in …, 2021 - frontiersin.org
Zika virus (ZIKV) received worldwide attention over the past decade when outbreaks of the
disease were found to be associated with severe neurological syndromes and congenital …

[HTML][HTML] Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

RJ Gestuveo, J Royle, CL Donald, DJ Lamont… - Nature …, 2021 - nature.com
The escalating global prevalence of arboviral diseases emphasizes the need to improve our
understanding of their biology. Research in this area has been hindered by the lack of …

[HTML][HTML] Comprehensive host-pathogen protein-protein interaction network analysis

B Khorsand, A Savadi, M Naghibzadeh - BMC bioinformatics, 2020 - Springer
Background Infectious diseases are a cruel assassin with millions of victims around the
world each year. Understanding infectious mechanism of viruses is indispensable for their …

[HTML][HTML] The journey of Zika to the developing brain

F Rombi, R Bayliss, A Tuplin, S Yeoh - Molecular biology reports, 2020 - Springer
Zika virus is a mosquito-borne Flavivirus originally isolated from humans in 1952. Following
its re-emergence in Brazil in 2015, an increase in the number of babies born with …

Synthesis and virucide activity on zika virus of 1, 2, 3-triazole-containing vanillin derivatives

JV da Silva Rodrigues, PAR Gazolla, I da Cruz Pereira… - Antiviral Research, 2023 - Elsevier
The Zika virus (ZIKV) is an arbovirus and belongs to the Flaviviridae family and Flavivirus
genus, with dissemination in the Americas. In Brazil, the predominant strain is the Asian …

Review of-omics studies on mosquito-borne viruses of the Flavivirus genus

RS Peinado, RJ Eberle, CC Pacca, RK Arni… - Virus Research, 2022 - Elsevier
Arboviruses are transmitted by arthropods (arthropod-borne virus) which can be mosquitoes
or other hematophagous arthropods, in which their life cycle occurs before transmission to …

[HTML][HTML] Coordination of Zika virus infection and viroplasm organization by microtubules and microtubule-organizing centers

RA Buchwalter, SC Ogden, SB York, L Sun, C Zheng… - Cells, 2021 - mdpi.com
Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital
microcephaly and other birth defects. Flaviviruses, including ZIKV, reorganize the …

[HTML][HTML] Virus-host protein-protein interactions as molecular drug targets for arboviral infections

M Bhutkar, V Singh, P Dhaka, S Tomar - Frontiers in Virology, 2022 - frontiersin.org
Arboviruses have the potential to spread quickly and cause a global health emergency.
These are RNA viruses that use RNA-dependent RNA polymerase (RdRp) for their …