Animal models of human neurodegenerative disease have been investigated for several
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …

To ensure tissue homeostasis the brain needs to be protected from blood-derived
fluctuations or pathogens that could affect its function. Therefore, the brain capillaries …

The Enteric Nervous System (ENS) is a large network of enteric neurons and glia that
regulates various processes in the gastrointestinal tract including motility, local blood flow …

Atherosclerosis is the most prevalent cause of cardiovascular disease-induced deaths
worldwide. Micro-and nano-bubbles (MNBs) have been developed as the vehicles for …

Genome-wide association studies identified Spen as a putative modifier of cardiac function,
however, the precise function of Spen in the cardiovascular system is not known yet. Here …

Self-transcribing active regulatory region sequencing (STARR-seq) and its variants have
been widely used to characterize enhancers. However, it has been reported that up to 87 …

Background: Work might cause severe physical stress associated with emotional overload,
especially among hospital employees. Objective: To identify risk factors for cardiovascular …

Introduction: In the last decade, our armamentarium of cardiovascular drug therapy has
expanded significantly. Using innovative functional genomics strategies such as genome …

In the human heart, the energy supplied by the production of ATP is predominately
accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel …

Introduction: The CK1 family is involved in a variety of physiological processes by regulating
different signaling pathways, including the Wnt/β-catenin, the Hedgehog and the p53 …