Zebrafish and medaka: important animal models for human neurodegenerative diseases
J Wang, H Cao - International journal of molecular sciences, 2021 - mdpi.com
Animal models of human neurodegenerative disease have been investigated for several
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
decades. In recent years, zebrafish (Danio rerio) and medaka (Oryzias latipes) have become …
[HTML][HTML] Development of the brain vasculature and the blood-brain barrier in zebrafish
C Quiñonez-Silvero, K Hübner, W Herzog - Developmental biology, 2020 - Elsevier
To ensure tissue homeostasis the brain needs to be protected from blood-derived
fluctuations or pathogens that could affect its function. Therefore, the brain capillaries …
fluctuations or pathogens that could affect its function. Therefore, the brain capillaries …
Zebrafish: a model organism for studying enteric nervous system development and disease
LE Kuil, RK Chauhan, WW Cheng… - Frontiers in Cell and …, 2021 - frontiersin.org
The Enteric Nervous System (ENS) is a large network of enteric neurons and glia that
regulates various processes in the gastrointestinal tract including motility, local blood flow …
regulates various processes in the gastrointestinal tract including motility, local blood flow …
Recent advances in micro-and nano-bubbles for atherosclerosis applications
Atherosclerosis is the most prevalent cause of cardiovascular disease-induced deaths
worldwide. Micro-and nano-bubbles (MNBs) have been developed as the vehicles for …
worldwide. Micro-and nano-bubbles (MNBs) have been developed as the vehicles for …
[HTML][HTML] Spen deficiency interferes with Connexin 43 expression and leads to heart failure in zebrafish
M Rattka, S Westphal, BM Gahr, S Just… - Journal of Molecular and …, 2021 - Elsevier
Genome-wide association studies identified Spen as a putative modifier of cardiac function,
however, the precise function of Spen in the cardiovascular system is not known yet. Here …
however, the precise function of Spen in the cardiovascular system is not known yet. Here …
[PDF][PDF] Underlying causes for prevalent false positives and false negatives in STARR-seq data
Self-transcribing active regulatory region sequencing (STARR-seq) and its variants have
been widely used to characterize enhancers. However, it has been reported that up to 87 …
been widely used to characterize enhancers. However, it has been reported that up to 87 …
[HTML][HTML] Health workers: cardiovascular risk and occupational stress
FO Ulguim, JDP Renner, HH Pohl… - Revista Brasileira de …, 2019 - ncbi.nlm.nih.gov
Background: Work might cause severe physical stress associated with emotional overload,
especially among hospital employees. Objective: To identify risk factors for cardiovascular …
especially among hospital employees. Objective: To identify risk factors for cardiovascular …
Streamlining drug discovery assays for cardiovascular disease using zebrafish
A Pott, W Rottbauer, S Just - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction: In the last decade, our armamentarium of cardiovascular drug therapy has
expanded significantly. Using innovative functional genomics strategies such as genome …
expanded significantly. Using innovative functional genomics strategies such as genome …
Long-chain acyl-carnitines interfere with mitochondrial ATP production leading to cardiac dysfunction in zebrafish
DD Park, BM Gahr, J Krause, W Rottbauer… - International Journal of …, 2021 - mdpi.com
In the human heart, the energy supplied by the production of ATP is predominately
accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel …
accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel …
Zebrafish as model system for the biological characterization of CK1 inhibitors
L Meier, BM Gahr, A Roth, A Gihring… - Frontiers in …, 2023 - frontiersin.org
Introduction: The CK1 family is involved in a variety of physiological processes by regulating
different signaling pathways, including the Wnt/β-catenin, the Hedgehog and the p53 …
different signaling pathways, including the Wnt/β-catenin, the Hedgehog and the p53 …