Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL
Much focus has been on the interaction of programmed cell death ligand 1 (PD-L1) on
malignant B cells with programmed cell death 1 (PD-1) on effector T cells in inhibiting …
malignant B cells with programmed cell death 1 (PD-1) on effector T cells in inhibiting …
The impact of EBV and HIV infection on the microenvironmental niche underlying H odgkin lymphoma pathogenesis
A Carbone, A Gloghini, A Caruso… - … Journal of Cancer, 2017 - Wiley Online Library
The pathogenesis of classical Hodgkin lymphoma (cHL) is still enigmatic, largely because its
tumor cells, the so‐called Hodgkin and Reed–Stenberg (HRS) cells, invariably reside in a …
tumor cells, the so‐called Hodgkin and Reed–Stenberg (HRS) cells, invariably reside in a …
[HTML][HTML] Primary and acquired resistance mechanisms to immune checkpoint inhibition in Hodgkin lymphoma
J Veldman, L Visser, A van den Berg… - Cancer treatment reviews, 2020 - Elsevier
Hodgkin lymphoma is a B cell derived malignancy characterized by a low number of tumor
cells within an environment consisting of inflammatory cells. Recently, immune checkpoint …
cells within an environment consisting of inflammatory cells. Recently, immune checkpoint …
Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration
PURPOSE Understanding the immunobiology of the 15% to 30% of patients with follicular
lymphoma (FL) who experience progression of disease within 24 months (POD24) remains …
lymphoma (FL) who experience progression of disease within 24 months (POD24) remains …
LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma
C Keane, SC Law, C Gould, S Birch… - Blood …, 2020 - ashpublications.org
Chimeric antigen receptor T-cell (CAR-T) therapy yields durable responses in patients with
relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). Cytokine release syndrome …
relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). Cytokine release syndrome …
The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma
Purpose: To investigate the relationship between the intra-tumoral T-cell receptor (TCR)
repertoire and the tumor microenvironment (TME) in de novo diffuse large B-cell lymphoma …
repertoire and the tumor microenvironment (TME) in de novo diffuse large B-cell lymphoma …
The tumour microenvironment is immuno‐tolerogenic and a principal determinant of patient outcome in EBV‐positive diffuse large B‐cell lymphoma
Abstract Objective Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV‐pos
DLBCL) is a recently identified entity. Data regarding outcome to frontline immuno …
DLBCL) is a recently identified entity. Data regarding outcome to frontline immuno …
Shared pathogenicity features and sequences between EBV, SARS-coV-2, and HLA class I molecule-binding motifs with a potential role in autoimmunity
Y Adiguzel, N Mahroum, S Muller, M Blank… - Clinical Reviews in …, 2023 - Springer
Epstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are extraordinary in their ability to activate autoimmunity as well as to induce diverse …
2) are extraordinary in their ability to activate autoimmunity as well as to induce diverse …
Genetics of immune response to Epstein-Barr virus: prospects for multiple sclerosis pathogenesis
J Huang, K Tengvall, I Bomfim Lima, AK Hedström… - Brain, 2024 - academic.oup.com
Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing
multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise …
multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise …
[HTML][HTML] The microenvironment in Epstein–Barr virus-associated malignancies
The Epstein–Barr virus (EBV) can cause a wide variety of cancers upon infection of different
cell types and induces a highly variable composition of the tumor microenvironment (TME) …
cell types and induces a highly variable composition of the tumor microenvironment (TME) …