Immunomodulatory biomaterials for tissue repair
R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
inflammatory response was once considered a detrimental force to be blunted or avoided, in …
Development of innovative biomaterials and devices for the treatment of cardiovascular diseases
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …
increasing burden of cardiovascular diseases has become a major public health problem …
Collagen-and hyaluronic acid-based hydrogels and their biomedical applications
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …
Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
A review of recent progress on collagen‐based biomaterials
M Zheng, X Wang, Y Chen, O Yue, Z Bai… - Advanced …, 2023 - Wiley Online Library
Since the 2010s, the demand for healthcare models has exceeded the prevailing resources
available due to the rapid increase in the aging population in China. However, a significant …
available due to the rapid increase in the aging population in China. However, a significant …
An adhesive hydrogel with “Load‐Sharing” effect as tissue bandages for drug and cell delivery
Hydrogels with adhesive properties have potential for numerous biomedical applications.
Here, the design of a novel, intrinsically adhesive hydrogel and its use in developing internal …
Here, the design of a novel, intrinsically adhesive hydrogel and its use in developing internal …
Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis …
Current treatments including drug therapy, medical device implantation, and organ
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …
Macrophage polarization in cardiac tissue repair following myocardial infarction
Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …
creating a substantial socio-economic burden as a result. Myocardial infarction is a …
Bioengineering artificial blood vessels from natural materials
Bioengineering an effective, small diameter (< 6 mm) artificial vascular graft for use in
bypass surgery when autologous grafts are unavailable remains a persistent challenge …
bypass surgery when autologous grafts are unavailable remains a persistent challenge …
Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery
D Zhu, J Hou, M Qian, D Jin, T Hao, Y Pan… - Nature …, 2021 - nature.com
Nitric oxide (NO) is a short-lived signaling molecule that plays a pivotal role in
cardiovascular system. Organic nitrates represent a class of NO-donating drugs for treating …
cardiovascular system. Organic nitrates represent a class of NO-donating drugs for treating …