Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

A review of recent progress on collagen‐based biomaterials

M Zheng, X Wang, Y Chen, O Yue, Z Bai… - Advanced …, 2023 - Wiley Online Library
Since the 2010s, the demand for healthcare models has exceeded the prevailing resources
available due to the rapid increase in the aging population in China. However, a significant …

An adhesive hydrogel with “Load‐Sharing” effect as tissue bandages for drug and cell delivery

J Chen, D Wang, LH Wang, W Liu, A Chiu… - Advanced …, 2020 - Wiley Online Library
Hydrogels with adhesive properties have potential for numerous biomedical applications.
Here, the design of a novel, intrinsically adhesive hydrogel and its use in developing internal …

Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis …

C Hu, W Liu, L Long, Z Wang, W Zhang, S He, L Lu… - Biomaterials, 2022 - Elsevier
Current treatments including drug therapy, medical device implantation, and organ
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …

Macrophage polarization in cardiac tissue repair following myocardial infarction

Y Kim, S Nurakhayev, A Nurkesh… - International journal of …, 2021 - mdpi.com
Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …

Bioengineering artificial blood vessels from natural materials

MJ Moore, RP Tan, N Yang, J Rnjak-Kovacina… - Trends in …, 2022 - cell.com
Bioengineering an effective, small diameter (< 6 mm) artificial vascular graft for use in
bypass surgery when autologous grafts are unavailable remains a persistent challenge …

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

D Zhu, J Hou, M Qian, D Jin, T Hao, Y Pan… - Nature …, 2021 - nature.com
Nitric oxide (NO) is a short-lived signaling molecule that plays a pivotal role in
cardiovascular system. Organic nitrates represent a class of NO-donating drugs for treating …