BDNF is a critical contributor to neuronal growth, development, learning, and memory.
Although extensively studied in the brain, BDNF is also expressed by primary afferent …

Abstract 6α, 7β-dihydroxy-vouacapan-17β-oic (tricyclic furanoid diterpene; DHVO) acid was
isolated from the hexane extract of Pterodon emarginatus fruits and evaluated for anti …

Hindpaw injection of dilute formalin produces brief (Phase 1) and persistent (Phase 2)
nociceptive responses in the rat. We recently showed that systemically-administered …

The important role of genetic factors in the mediation of sensitivity to pain and pain inhibition
is being increasingly appreciated. In an attempt to systematically study the genotypic …

Many studies indicate that blood pressure control systems can attenuate pain (hypoalgesia)
of short duration; however, we recently found exaggerated nociceptive responses …

Neuropathy will afflict over half of the approximately 350 million people worldwide who
currently suffer from diabetes and around one-third of diabetic patients with neuropathy will …

To test the hypothesis that administration of neuropeptide Y (NPY) to the spinal cord reduces
inflammatory pain, we evaluated the effects of intrathecal NPY on behavioral and …

In this study, the suppressive effects of BmK IT2, a kind of Na+ channel‐specific modulator
from the venom of the scorpion Buthus martensi Karsch, on biphasic nociceptive behavior in …

IMPLICATIONS: Presentation of essential hypertension should be considered when opioid
regimens are planned both during surgery (to minimize cardiovascular complications) and …

The purpose of this animal investigation was to compare behavioral responses with spinal
Fos-like immunoreactivity (FLI) after pre-versus postformalin administration of anesthetic …