Cellular mechanisms of taste transduction

MS Herness, TA Gilbertson - Annual review of physiology, 1999 - annualreviews.org
▪ Abstract Taste receptor cells respond to gustatory stimuli using a complex arrangement of
receptor molecules, signaling cascades, and ion channels. When stimulated, these cells …

A metabotropic glutamate receptor variant functions as a taste receptor

N Chaudhari, AM Landin, SD Roper - Nature neuroscience, 2000 - nature.com
Sensory transduction for many taste stimuli such as sugars, some bitter compounds and
amino acids is thought to be mediated via G protein-coupled receptors (GPCRs), although …

Biology of taste buds and the clinical problem of taste loss

GM Nelson - The Anatomical Record: An Official Publication of …, 1998 - Wiley Online Library
Taste buds are the anatomical structures that mediate the sense of taste. They comprise
taste cells and nerve fibers within specialized epithelial structures. Taste cells are …

Taste receptor for umami (monosodium glutamate) taste

N Chaudhari, SD Roper - US Patent 6,608,176, 2003 - Google Patents
A metabotropic glutamate taste receptor having a molecular weight of approximately 68 kDa,
encoded by a cDNA sequence having the mRNA sequence of SEQ ID NO: 1 is disclosed …

[HTML][HTML] Taste buds have a cyclic nucleotide-activated channel, CNGgust

T Misaka, Y Kusakabe, Y Emori, T Gonoi, S Arai… - Journal of Biological …, 1997 - ASBMB
Cyclic nucleotide-gated (CNG) channels have been characterized as important factors
involved in physiological processes including sensory reception for vision and olfaction. The …

[HTML][HTML] Identification of two α-subunit species of GTP-binding proteins, Gα15 and Gαq, expressed in rat taste buds

Y Kusakabe, E Yamaguchi, K Tanemura… - … et Biophysica Acta (BBA …, 1998 - Elsevier
We cloned cDNAs for two G protein α-subunits belonging to the Gαq family, each capable of
activating PLCβ, from rat tongue. One is a Gαq in the narrow sense, and the other, termed rat …

New GPCRs from a human lingual cDNA library

JC Gaudin, L Breuils, T Haertle - Chemical senses, 2001 - academic.oup.com
Sweet and bitter taste perception involve G protein coupled receptors (GPCRs) present at
the taste receptor cell surface. It is likely that various mechanisms are active and various …

Cross-adaptation and molecular modeling study of receptor mechanisms common to four taste stimuli in humans

N Froloff, E Lloret, JM Martinez, A Faurion - Chemical senses, 1998 - academic.oup.com
Psychophysical cross-adaptation experiments were performed with two carbohydrates,
sucrose (SUC) and fructose (FRU), and two sweeteners, acesulfame-K (MOD) and dulcin …

Studies on taste: molecular biology and food science

K Abe - Bioscience, biotechnology, and biochemistry, 2008 - academic.oup.com
Taste is indispensable for vertebrate to find a proper way of living by selection of foods at
their discretion. It is also a mainstay in the construction of human culture and the food …

[HTML][HTML] S100B-modulated Ca2+-dependent ROS-GC1 transduction machinery in the gustatory epithelium: a new mechanism in gustatory transduction

T Duda, RK Sharma - FEBS letters, 2004 - Elsevier
Gustatory transduction is a biochemical process by which the gustatory signal generates the
electric signal. The microvilli of the taste cells in the gustatory epithelium are the sites of …