Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways

AS Doghish, HA El-Mahdy, A Ismail, M Hegazy… - … -Research and Practice, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma

L Yip, L Kelly, Y Shuai, MJ Armstrong… - Annals of surgical …, 2011 - Springer
Background Papillary thyroid carcinoma (PTC) has relatively indolent behavior, although
some tumors recur and disseminate to distant sites. The aggressive biological behavior of …

[HTML][HTML] RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action

J Masliah-Planchon, S Garinet, E Pasmant - Oncotarget, 2016 - ncbi.nlm.nih.gov
The highly conserved RAS-mitogen activated protein kinase (MAPK) signaling pathway is
involved in a wide range of cellular processes including differentiation, proliferation, and …

MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer

MV Geraldo, AS Yamashita, ET Kimura - Oncogene, 2012 - nature.com
MicroRNAs (miRNA) are small non-coding RNAs involved in post-transcriptional gene
regulation that have crucial roles in several types of tumors, including papillary thyroid …

MicroRNA‐222 and MicroRNA‐146b are tissue and circulating biomarkers of recurrent papillary thyroid cancer

JC Lee, JT Zhao, RJ Clifton‐Bligh, A Gill, JS Gundara… - Cancer, 2013 - Wiley Online Library
BACKGROUND Papillary thyroid cancer (PTC) persistence or recurrence and the need for
long‐term surveillance can cause significant inconvenience and morbidity in patients …

Molecular pathology of thyroid tumours of follicular cells: a review of genetic alterations and their clinicopathological relevance

G Acquaviva, M Visani, A Repaci, KJ Rhoden… - …, 2018 - Wiley Online Library
Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular
pathology of thyroid tumours originating from follicular cells has greatly advanced in the past …

[HTML][HTML] A ten-microRNA expression signature predicts survival in glioblastoma

S Srinivasan, IRP Patric, K Somasundaram - PloS one, 2011 - journals.plos.org
Glioblastoma (GBM) is the most common and aggressive primary brain tumor with very poor
patient median survival. To identify a microRNA (miRNA) expression signature that can …

MicroRNAs as biomarkers in thyroid carcinoma

M Celano, F Rosignolo, V Maggisano… - … journal of genomics, 2017 - Wiley Online Library
Optimal management of patients with thyroid cancer requires the use of sensitive and
specific biomarkers. For early diagnosis and effective follow‐up, the currently available …

Differential MicroRNA‐Signatures in Thyroid Cancer Subtypes

K Santiago, Y Chen Wongworawat… - Journal of Oncology, 2020 - Wiley Online Library
Thyroid cancer is one of the most common endocrine cancers, with an increasing trend in
the last few decades. Although papillary thyroid cancer is the most frequent subtype …