Cornerstone Cellular pathways for metabolic disorders and Diabetes Mellitus: non-coding RNAs, wnt signaling, and AMPK

K Maiese - Cells, 2023 - mdpi.com
Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …

Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice

HX Chen, XC Wang, HT Hou, J Wang, Q Yang… - International Journal of …, 2023 - Elsevier
Protein post-translational modifications (PTMs) are important regulators of protein functions
and produce proteome complexity. SIRT1 has NAD+-dependent deacylation of acyl-lysine …

Protective Role of Endothelial SIRT1 in Deep Vein Thrombosis and Hypoxia-induced Endothelial Dysfunction Mediated by NF-κB Deacetylation

P Tang, Y Wang, X Yang, Z Wu, W Chen, Y Ye, Y Jiang… - Inflammation, 2023 - Springer
Venous hypoxia is considered as the major pathogenetic mechanism linking blood flow
stagnancy with deep vein thrombosis (DVT). Our previous study showed that activating …

Role of sirtuins in attenuating plaque vulnerability in atherosclerosis

P Velpuri, V Rai, DK Agrawal - Molecular and Cellular Biochemistry, 2024 - Springer
Atherosclerosis is characterized by the development of intimal plaque, thrombosis, and
stenosis of the vessel lumen causing decreased blood flow and hypoxia precipitating …

Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD

TB Opstad, B Papotti, S Åkra, CH Hansen… - Journal of Translational …, 2023 - Springer
Background Inflammation in cardiac adipose tissue (AT) is associated with atherosclerosis.
We investigated whether the epicardial-, pericardial and pre-sternal subcutaneous AT (EAT …

[图书][B] Biology of Vascular Smooth Muscle

Y Gao - 2017 - Springer
The blood vessels are tubular structured consisting of three layers: the tunica intima, the
tunica media, and the tunica adventitia. The tunica intima is the innermost layer of the …

Soybean-Derived Tripeptide Leu–Ser–Trp (LSW) Protects Human Vascular Endothelial Cells from TNFα-Induced Oxidative Stress and Inflammation via Modulating …

H Fan, KS Bhullar, Z Wang, J Wu - Foods, 2022 - mdpi.com
Soybean is a rich source of high-quality proteins and an excellent food source of bioactive
peptides. A tripeptide, Leu–Ser–Trp (LSW), was previously identified from soybean as an …

Evaluating the inhibitory effect of resveratrol on the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice

SAES El-Sayed, ES El-Alfy… - Frontiers in …, 2023 - frontiersin.org
Introduction: Histone post-translational modification is one of the most studied factors
influencing epigenetic regulation of protozoan parasite gene expression, which is mediated …

[HTML][HTML] The theranostic value of acetylation gene signatures in obstructive sleep apnea derived by machine learning

Y Wang, J Zhang, Y He, Z Pan, X Zhang, P Liu… - Computers in Biology …, 2023 - Elsevier
Epigenetic modifications are implicated in the onset and progression of obstructive sleep
apnea (OSA) and its complications through their bidirectional relationship with long-term …

Inverse correlation between the expression of AMPK/SIRT1 and NAMPT in psoriatic skin: A pilot study

F D'Amico, G Costantino, L Salvatorelli… - Advances in Medical …, 2022 - Elsevier
Purpose Epidermal hyperplasia and the involvement of immune cells characterize the
clinical picture of psoriasis. Among the several factors involved, attention has been focused …