Plasma Exosomal miR-199a-5p Derived from Preeclampsia with Severe Features Impairs Endothelial Cell Function via Targeting SIRT1
Z Chen, M Wu, H Huang, H Tao, L Zou, Q Luo - Reproductive Sciences, 2022 - Springer
Preeclampsia (PE) is a pregnancy complication with high maternal and fetal morbidity and
mortality rates. During pregnancy, the concentration of exosomes in the maternal blood …
mortality rates. During pregnancy, the concentration of exosomes in the maternal blood …
Sirtuin 2 in vascular ageing: the forsaken child?
YM Puspitasari - European Heart Journal, 2023 - academic.oup.com
Arterial stiffness holds clinical significance as an independent predictor for CV events and
stroke. 12, 13 One well-known component contributing to the development of age-related …
stroke. 12, 13 One well-known component contributing to the development of age-related …
Serum proteomic biomarker investigation of vascular depression using data-independent acquisition: a pilot study
L Lan, S Peng, R Zhang, H He, Y Yang, B Xi… - Frontiers in Aging …, 2024 - frontiersin.org
Background Vascular depression (VaD) is a depressive disorder closely associated with
cerebrovascular disease and vascular risk factors. It remains underestimated owing to …
cerebrovascular disease and vascular risk factors. It remains underestimated owing to …
[HTML][HTML] Dental pulp stem cells ameliorate D-galactose-induced cardiac ageing in rats
G El-Akabawy, SOF El-Kersh, AOFO El-Kersh, SN Amin… - PeerJ, 2024 - peerj.com
Background Ageing is a key risk factor for cardiovascular disease and is linked to several
alterations in cardiac structure and function, including left ventricular hypertrophy and …
alterations in cardiac structure and function, including left ventricular hypertrophy and …
[HTML][HTML] Ginsenoside Rb1 prevents age-related endothelial senescence by modulating SIRT1/caveolin-1/enos signaling pathway
B Zhou, G Shi, D Xie, X Zhao, B Hao, D Liu, M Wang… - Heliyon, 2024 - cell.com
Background Advancing age is one of the independent risk factors for cardiovascular
disorders. The Compendium of Materia Medica, a classic book on traditional Chinese …
disorders. The Compendium of Materia Medica, a classic book on traditional Chinese …
Association of SIRT1 with metabolic parameters and aging rate
O Kolesnikova, O Zaprovalna… - Biomedical …, 2023 - bmrat.biomedpress.org
Introduction: SIRT1 has attracted great interest due to its role as a regulator of longevity, and
its therapeutic potential for the prevention and treatment of aging and age-related …
its therapeutic potential for the prevention and treatment of aging and age-related …
Cellular and molecular determinants of arterial aging
P Lacolley, P Challande, V Regnault, EG Lakatta… - Early Vascular Aging …, 2024 - Elsevier
A number of key signaling pathways are highly relevant to early vascular aging. These are
overviewed here to provide a context for understanding the initiation and progression of …
overviewed here to provide a context for understanding the initiation and progression of …
[HTML][HTML] The role of nitric oxide on the antiarrhythmic effects of ketamine/xylazine in a rat model of acute cardiac ischemia-reperfusion
A Imani, SF Rajani, K Rakhshan, M Faghihi… - Current Research in …, 2022 - Elsevier
The prevalence of ventricular arrhythmias during general anesthesia is about 70%. In
experimental studies on the antiarrhythmic effects of different agents, using anesthetic drugs …
experimental studies on the antiarrhythmic effects of different agents, using anesthetic drugs …
[HTML][HTML] Waterpipe Smoke Inhalation Induces Lung Injury and Aortic Endothelial Dysfunction in Mice
Waterpipe tobacco smoking (WPS) inhalation has been shown to trigger endothelial
dysfunction and atherosclerosis. However, the mechanisms underlying these effects are still …
dysfunction and atherosclerosis. However, the mechanisms underlying these effects are still …
Recent insights concerning autophagy and endothelial cell nitric oxide generation
Although endothelial cell (EC) dysfunction contributes to the etiology of more diseases than
any other tissue in the body, EC metabolism is an understudied therapeutic target. Evidence …
any other tissue in the body, EC metabolism is an understudied therapeutic target. Evidence …