[HTML][HTML] The interaction between TERT promoter mutation and MGMT promoter methylation on overall survival of glioma patients: a meta-analysis

HG Vuong, TQ Nguyen, TNM Ngo, HC Nguyen… - BMC cancer, 2020 - Springer
Background There are controversial results concerning the prognostic implication of TERT
promoter mutation in glioma patients concerning MGMT status. In this meta-analysis, we …

Family caregivers' level of mastery predicts survival of patients with glioblastoma: a preliminary report

FW Boele, CW Given, BA Given, HS Donovan… - Cancer, 2017 - Wiley Online Library
BACKGROUND Glioblastoma multiforme (GBM) is associated with a poor prognosis, and
patients rely heavily on family caregivers for physical and emotional support. The capability …

Surgical treatment of glioblastoma in the elderly: the impact of complications

M Karsy, N Yoon, L Boettcher, R Jensen, L Shah… - Journal of neuro …, 2018 - Springer
The diagnosis of glioblastoma (GBM) often carries a dismal prognosis, with a median
survival of 14.6 months. A particular challenge is the diagnosis of GBM in the elderly …

[HTML][HTML] Brain metastases in the elderly–Impact of residual tumor volume on overall survival

L Baumgart, AK Aftahy, A Anetsberger… - Frontiers in …, 2023 - frontiersin.org
Background: Due to demographic changes and an increased incidence of cancer with age,
the number of patients with brain metastases (BM) is constantly increasing, especially …

Interesting different survival status of musicians with malignant cerebral tumors

ER Gasenzer, A Kanat, V Ozdemir… - British journal of …, 2020 - Taylor & Francis
Introduction: The education of a musician may have an effect on the neuronal functions and
organization of the brain, promote brain plasticity, resulting in functional and structural …

[HTML][HTML] Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/p38 MAPK signaling pathway

J Yang, JN Zhang, WL Chen, GS Wang, Q Mao, SQ Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
We investigated the effects of aquaporin 5 (AQP5) gene silencing on the proliferation,
migration and apoptosis of human glioma cells through regulating the EGFR/ERK/p38MAPK …

Is age an additional factor in the treatment of elderly patients with glioblastoma? A new stratification model: an Italian Multicenter Study

T Ius, T Somma, R Altieri, FF Angileri… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE Approximately half of glioblastoma (GBM) cases develop in geriatric patients,
and this trend is destined to increase with the aging of the population. The optimal strategy …

Hospice utilization in patients with malignant gliomas

D Forst, E Adams, R Nipp, A Martin… - Neuro …, 2018 - academic.oup.com
Background Despite recommendations from professional organizations supporting early
hospice enrollment for patients with cancer, little research exists regarding end-of-life (EOL) …

[HTML][HTML] Characteristics and outcomes of elderly patients with diffuse gliomas: a multi-institutional cohort study by Kansai Molecular Diagnosis Network for CNS …

T Sasaki, J Fukai, Y Kodama, T Hirose, Y Okita… - Journal of Neuro …, 2018 - Springer
Introduction This study investigates the current state of clinical practice and molecular
analysis for elderly patients with diffuse gliomas and aims to elucidate treatment outcomes …

[HTML][HTML] High grade glioma treatment in elderly people: is it different than in younger patients? Analysis of surgical management guided by an intraoperative …

GMV Barbagallo, R Altieri, M Garozzo, M Maione… - Frontiers in …, 2021 - frontiersin.org
Objective Age is considered a negative prognostic factor for High Grade Gliomas (HGGs)
and many neurosurgeons remain skeptical about the benefits of aggressive treatment. New …