Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …

Background & Aims Machine perfusion is a novel method intended to optimize livers before
transplantation. However, its effect on morbidity within a 1-year period after transplantation …

The mononuclear phagocyte system (MPS, eg, liver, spleen) is often treated as a “blackbox”
by nanoresearchers in translating nanomedicines. Often, most of the injected nanomaterials …

Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

Hepatic ischemia–reperfusion (IR) injury is a common clinical issue lacking effective therapy
and validated pharmacological targets. Here, using integrative'omics' analysis, we identified …

Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …

The liver possesses the unique ability to regenerate within a short period of time, a feature
that has led to the development of innovative strategies in liver surgery and transplantation …