Role of liver sinusoidal endothelial cells in liver diseases
J Gracia-Sancho, E Caparrós… - Nature reviews …, 2021 - nature.com
Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …
other capillaries, they lack an organized basement membrane and have cytoplasm that is …
Ischaemia–reperfusion injury in liver transplantation—from bench to bedside
Y Zhai, H Petrowsky, JC Hong, RW Busuttil… - Nature reviews …, 2013 - nature.com
Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …
resection and transplantation, is a dynamic process that involves the two interrelated phases …
[HTML][HTML] A multicenter randomized-controlled trial of hypothermic oxygenated perfusion (HOPE) for human liver grafts before transplantation
A Schlegel, M Mueller, X Muller, J Eden… - Journal of …, 2023 - Elsevier
Background & Aims Machine perfusion is a novel method intended to optimize livers before
transplantation. However, its effect on morbidity within a 1-year period after transplantation …
transplantation. However, its effect on morbidity within a 1-year period after transplantation …
Ceria nanoparticles meet hepatic ischemia‐reperfusion injury: the perfect imperfection
The mononuclear phagocyte system (MPS, eg, liver, spleen) is often treated as a “blackbox”
by nanoresearchers in translating nanomedicines. Often, most of the injected nanomaterials …
by nanoresearchers in translating nanomedicines. Often, most of the injected nanomaterials …
[HTML][HTML] Inflammasome-mediated inflammation in liver ischemia-reperfusion injury
MB Jiménez-Castro, ME Cornide-Petronio… - Cells, 2019 - mdpi.com
Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …
procedures including hepatic resection and liver transplantation, and represents the main …
[HTML][HTML] Hepatic ischemia reperfusion injury: A systematic review of literature and the role of current drugs and biomarkers
M Cannistrà, M Ruggiero, A Zullo, G Gallelli… - International journal of …, 2016 - Elsevier
Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …
[HTML][HTML] Hepatic ischemia and reperfusion injury: effects on the liver sinusoidal milieu
C Peralta, MB Jiménez-Castro, J Gracia-Sancho - Journal of hepatology, 2013 - Elsevier
Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …
procedures including hepatic resection and liver transplantation, and represents the main …
An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury
XJ Zhang, XU Cheng, ZZ Yan, J Fang, X Wang… - Nature medicine, 2018 - nature.com
Hepatic ischemia–reperfusion (IR) injury is a common clinical issue lacking effective therapy
and validated pharmacological targets. Here, using integrative'omics' analysis, we identified …
and validated pharmacological targets. Here, using integrative'omics' analysis, we identified …
Role of Kupffer cells in host defense and liver disease
M Bilzer, F Roggel, AL Gerbes - Liver International, 2006 - Wiley Online Library
Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …
Strategies for safer liver surgery and partial liver transplantation
PA Clavien, H Petrowsky… - New England Journal …, 2007 - Mass Medical Soc
The liver possesses the unique ability to regenerate within a short period of time, a feature
that has led to the development of innovative strategies in liver surgery and transplantation …
that has led to the development of innovative strategies in liver surgery and transplantation …