[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Obesity as a disease

J Upadhyay, O Farr, N Perakakis, W Ghaly… - Medical …, 2018 - medical.theclinics.com
Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …

Genetic markers of type 2 diabetes: Progress in genome‐wide association studies and clinical application for risk prediction: 2 型糖尿病的遗传标记: 风险预测的全 …

X Wang, G Strizich, Y Hu, T Wang… - Journal of …, 2016 - Wiley Online Library
摘要2 型糖尿病已经成为全球公共卫生的主要挑战. 迄今为止, 通过全基因组关联研究(genome‐
wide association studies, GWAS) 总共已经鉴定出了83 个2 型糖尿病易感位点. 为了发现2 …

Trans-omics: how to reconstruct biochemical networks across multiple 'omic'layers

K Yugi, H Kubota, A Hatano, S Kuroda - Trends in biotechnology, 2016 - cell.com
We propose 'trans-omic'analysis for reconstructing global biochemical networks across
multiple omic layers by use of both multi-omic measurements and computational data …

Monogenic diabetes: what it teaches us on the common forms of type 1 and type 2 diabetes

Y Yang, L Chan - Endocrine reviews, 2016 - academic.oup.com
To date, more than 30 genes have been linked to monogenic diabetes. Candidate gene and
genome-wide association studies have identified> 50 susceptibility loci for common type 1 …

Personalized medicine in diabetes mellitus: current opportunities and future prospects

JW Kleinberger, TI Pollin - Annals of the New York Academy of …, 2015 - Wiley Online Library
Diabetes mellitus affects approximately 382 million individuals worldwide and is a leading
cause of morbidity and mortality. Over 40 and nearly 80 genetic loci influencing susceptibility …

Prevalence of and risk factors for type 2 diabetes mellitus in Vietnam: a systematic review

CT Nguyen, NM Pham, AH Lee… - Asia Pacific Journal of …, 2015 - journals.sagepub.com
This systematic review examined trends in the prevalence of type 2 diabetes mellitus
(T2DM) and identified its risk factors among adults in Vietnam. PubMed, Web of Science …

Genetic predisposition in type 2 diabetes: a promising approach toward a personalized management of diabetes

MM Sirdah, NS Reading - Clinical Genetics, 2020 - Wiley Online Library
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

[HTML][HTML] Classification and diagnosis of diabetes

SM Genuth, JP Palmer, DM Nathan - 2021 - europepmc.org
The classification of diabetes was originally limited to only two categories called juvenile-
onset diabetes mellitus, now known as type 1 diabetes mellitus, and adult-onset diabetes …

Genetic footprints of assortative mating in the Japanese population

K Yamamoto, K Sonehara, S Namba… - Nature Human …, 2023 - nature.com
Assortative mating (AM) is a pattern characterized by phenotypic similarities between mating
partners. Detecting the evidence of AM has been challenging due to the lack of large-scale …