The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Randomized trial of metformin, ivermectin, and fluvoxamine for Covid-19

CT Bramante, JD Huling, CJ Tignanelli… - … England Journal of …, 2022 - Mass Medical Soc
Background Early treatment to prevent severe coronavirus disease 2019 (Covid-19) is an
important component of the comprehensive response to the severe acute respiratory …

Metformin for treatment of acute COVID-19: systematic review of clinical trial data against SARS-CoV-2

SM Erickson, SL Fenno, N Barzilai, G Kuchel… - Diabetes …, 2023 - Am Diabetes Assoc
BACKGROUND Observational and preclinical data suggest metformin may prevent severe
coronavirus disease 2019 (COVID-19) outcomes. PURPOSE We conducted a systematic …

Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis

NN Nguyen, DS Ho, HS Nguyen, DKN Ho, HY Li… - Metabolism, 2022 - Elsevier
Background Diabetes is an independent predictor of poor outcomes in patients with COVID-
19. We compared the effects of the preadmission use of antidiabetic medications on the in …

Risk factors for COVID-19 case fatality rate in people with type 1 and type 2 diabetes mellitus: A nationwide retrospective cohort study of 235,248 patients in the …

MV Shestakova, OK Vikulova, AR Elfimova… - Frontiers in …, 2022 - frontiersin.org
The aim To study the association of demographic, clinical, and laboratory factors and the
use of glucose-lowering drugs and anti-coronavirus disease (COVID-19) vaccination with …

Angiotensin-converting enzyme 2 expression and severity of SARS-CoV-2 infection

S Alabsi, A Dhole, S Hozayen, SA Chapman - Microorganisms, 2023 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2), first discovered in 2000, serves as an important
counterregulatory enzyme to the angiotensin II-mediated vasoconstrictive, pro-inflammatory …

[HTML][HTML] Контроль гликемии и выбор антигипергликемической терапии у пациентов с сахарным диабетом 2 типа и COVID-19: консенсусное решение совета …

ИИ Дедов, НГ Мокрышева, МВ Шестакова… - Сахарный …, 2022 - cyberleninka.ru
С декабря 2019 г. в мире активно распространяется опасное вирусное заболевание-
COVID-19, вызванное новым РНК-коронавирусом SARS-COV-2. Основным …

[HTML][HTML] Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney

V Miguel, C Rey-Serra, J Tituaña, B Sirera… - Redox Biology, 2023 - Elsevier
Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019
(COVID-19) pandemic. It is the final outcome of the acute respiratory distress syndrome …

Is metformin use associated with low mortality in patients with type 2 diabetes mellitus hospitalized for COVID-19? a multivariable and propensity score-adjusted meta …

Z Ma, M Krishnamurthy - Plos one, 2023 - journals.plos.org
Background Coronavirus disease 2019 (COVID-19) is a new pandemic that the entire world
is facing since December of 2019. Increasing evidence has shown that metformin is linked to …

Mechanisms of ageing: growth hormone, dietary restriction, and metformin

J Khan, I Pernicova, K Nisar… - The Lancet Diabetes & …, 2023 - thelancet.com
Tackling the mechanisms underlying ageing is desirable to help to extend the duration and
improve the quality of life. Life extension has been achieved in animal models by …