As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …

Cells in tissues experience a plethora of forces that regulate their fate and modulate
development and homeostasis. Cells sense mechanical cues through localized …

Fibrotic disease is caused by the continuous deposition of extracellular matrix by persistently
activated fibroblasts (also known as myofibroblasts), even after the resolution of the injury …

The angiotensin-converting enzyme 2 (ACE2) is the receptor for the three coronaviruses
HCoV-NL63, SARS-CoV, and SARS-CoV-2. ACE2 is involved in the regulation of the renin …

Mesenchymal stem cells (MSCs) have been increasingly recognized as a resource for
disease treatment and regenerative medicine. Meanwhile, the unique chemical and physical …

Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …

Embryoid bodies (EBs) resemble self-organizing aggregates of pluripotent stem cells that
recapitulate some aspects of early embryogenesis. Within few days, the cells undergo a …

Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …

With the lack of minimally invasive tools for probing neuronal systems across spatiotemporal
scales, understanding the working mechanism of the nervous system and limited …

Direct cardiac reprogramming has emerged as a promising therapeutic approach for cardiac
regeneration. Full chemical reprogramming with small molecules to generate …