[HTML][HTML] Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

Role of Toll‐like receptors in the pathogenesis of COVID‐19

S Khanmohammadi, N Rezaei - Journal of medical virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has led to a pandemic since March 2020. The …

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

C Xu, J Huang, Y Jiang, S He, C Zhang… - Nature Biomedical …, 2023 - nature.com
Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

[HTML][HTML] TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines

M Zheng, R Karki, EP Williams, D Yang… - Nature …, 2021 - nature.com
The innate immune response is critical for recognizing and controlling infections through the
release of cytokines and chemokines. However, severe pathology during some infections …

[HTML][HTML] Detection of viral infections by innate immunity

M Carty, C Guy, AG Bowie - Biochemical pharmacology, 2021 - Elsevier
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …

Phagocytosis checkpoints as new targets for cancer immunotherapy

M Feng, W Jiang, BYS Kim, CC Zhang, YX Fu… - Nature Reviews …, 2019 - nature.com
Cancer immunotherapies targeting adaptive immune checkpoints have substantially
improved patient outcomes across multiple metastatic and treatment-refractory cancer types …

[HTML][HTML] Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

B Bahmani, H Gong, BT Luk, KJ Haushalter… - Nature …, 2021 - nature.com
Intratumoral immunotherapy is an emerging modality for the treatment of solid tumors. Toll-
like receptor (TLR) agonists have shown promise for eliciting immune responses, but …

The infant gut virome is associated with preschool asthma risk independently of bacteria

C Leal Rodríguez, SA Shah, MA Rasmussen… - Nature Medicine, 2024 - nature.com
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …

Respiratory epithelial cell responses to SARS-CoV-2 in COVID-19

JP Bridges, EK Vladar, H Huang, RJ Mason - Thorax, 2022 - thorax.bmj.com
COVID-19 has different clinical stages, and effective therapy depends on the location and
extent of the infection. The purpose of this review is to provide a background for …

[HTML][HTML] A candidate multi-epitope vaccine against SARS-CoV-2

T Kar, U Narsaria, S Basak, D Deb, F Castiglione… - Scientific reports, 2020 - nature.com
In the past two decades, 7 coronaviruses have infected the human population, with two
major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012 …