[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders

L Mitrea, SA Nemeş, K Szabo, BE Teleky… - Frontiers in …, 2022 - frontiersin.org
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …

Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future

JL Silverman, A Thurm, SB Ethridge… - Genes, brain and …, 2022 - Wiley Online Library
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …

[HTML][HTML] Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice

CW Lee, LF Hsu, IL Wu, YL Wang, WC Chen… - Journal of hazardous …, 2022 - Elsevier
Microplastics (MPs) pollution has become a serious environmental issue worldwide, but its
potential effects on health remain unknown. The administration of polystyrene MPs (PS …

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders

JA Jiménez, MJ Zylka - Journal of neurodevelopmental disorders, 2021 - Springer
Research with rodents is crucial for expanding our understanding of genetic and
environmental risk factors for neurodevelopmental disorders (NDD). However, there is …

[HTML][HTML] Encore: Behavioural animal models of stress, depression and mood disorders

A Petković, D Chaudhury - Frontiers in behavioral neuroscience, 2022 - frontiersin.org
Animal studies over the past two decades have led to extensive advances in our
understanding of pathogenesis of depressive disorders. Among these, rodent behavioural …

Oxidative stress as a common key event in developmental neurotoxicity

Y Nishimura, Y Kanda, H Sone… - Oxidative medicine and …, 2021 - Wiley Online Library
The developing brain is extremely sensitive to many chemicals. Perinatal exposure to
neurotoxicants has been implicated in several neurodevelopmental disorders, including …

Profiling DNA break sites and transcriptional changes in response to contextual fear learning

RT Stott, O Kritsky, LH Tsai - PLoS One, 2021 - journals.plos.org
Neuronal activity generates DNA double-strand breaks (DSBs) at specific loci in vitro and
this facilitates the rapid transcriptional induction of early response genes (ERGs) …

A neurodevelopment approach for a transitional model of early onset schizophrenia

D De Berardis, S De Filippis, G Masi, S Vicari… - Brain Sciences, 2021 - mdpi.com
In the last decades, the conceptualization of schizophrenia has dramatically changed,
moving from a neurodegenerative process occurring in early adult life to a …

Mental health of UK firefighters

TAM Wolffe, A Robinson, A Clinton, L Turrell… - Scientific reports, 2023 - nature.com
Exposure to trauma, high-stress situations, and disrupted sleep are well known risk factors
affecting firefighters' mental health. Little is known about the association between firefighters' …

Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD

JJ Walsh, P Llorach, DF Cardozo Pinto… - …, 2021 - nature.com
Autism spectrum disorder (ASD) is a common set of heterogeneous neurodevelopmental
disorders resulting from a variety of genetic and environmental risk factors. A core feature of …