Summary Type 1 diabetes (T1D) is widely considered to result from the autoimmune
destruction of insulin-producing β cells. This concept has been a central tenet for decades of …

Background Enteroviruses are routinely detected with molecular methods within large
cohorts that are at risk of type 1 diabetes. We aimed to examine the association between …

Previous studies showed a low-grade enterovirus infection in the pancreatic islets of patients
with newly diagnosed type 1 diabetes (T1D). In the Diabetes Virus Detection (DiViD) …

The evidence for an association between coxsackievirus B (CVB) infection, pancreatic islet
autoimmunity, and clinical type 1 diabetes is increasing. Results from prospective cohorts …

Type 1 diabetes results from the poorly understood process of islet autoimmunity, which
ultimately leads to the loss of functional pancreatic beta cells. Mounting evidence supports …

Epstein-Barr virus (EBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are extraordinary in their ability to activate autoimmunity as well as to induce diverse …

Aims/hypothesis Infection with coxsackie B viruses (CVBs) can cause diseases ranging from
mild common cold-type symptoms to severe life-threatening conditions. CVB infections are …

Background At diagnosis of Type 1 Diabetes (T1D), 30% of the beta cells are dormant, ie
alive, but inactive. This could reduce beta cell destruction, as cellular stress contributes to …

Abstract Type 1 diabetes (T1D), a severe disease requiring intensive insulin treatment,
carries an increased risk for complications and reduced lifespan. Certain viruses have been …

The human genome comprises 8% of endogenous retroviruses (HERVs). Though HERVS
contribute to physiological functions, copies retained pathogenic potential. The HERV-W …