Challenging skeletal repairs are frequently seen in patients experiencing systemic
inflammation. To tackle the complexity and heterogeneity of the skeletal repair process, we …

The availability of large human datasets for genome-wide association studies (GWAS) and
the advancement of sequencing technologies have boosted the identification of genetic …

It is a well-known fact that physical activity benefits people of all age groups. However,
highly intensive training, maladaptation, improper equipment, and lack of sufficient rest lead …

Abstract N6-methyladenosine (m 6 A) is the most prevalent modification in the eukaryotic
transcriptome and has a wide range of functions in coding and noncoding RNAs. It affects …

Osteoporosis is a common debilitating bone disease characterized by loss of bone mass
and degradation of the bone architecture, which is primarily driven by dysregulated …

Mesenchymal stem cells (MSCs) have been the most frequent stem cell used in clinical trials
due to their easy isolation from multiple adult tissues, their ability to home into the injury …

Osteoporosis is an age‐related metabolic bone disease. Hence, osteoporotic patients might
suffer from molecular features of accelerated aging, which is generally reflected by specific …

The aim of this work was to determine whether miR-455-3p regulates DNA methylation
during chondrogenic differentiation of hMSCs. The expression of miR-455-3p and de novo …

Mechanisms of cellular and nuclear mechanosensation are unclear, partially because of a
lack of methods that can reveal dynamic processes. Here, we present a new concept for a …

Long noncoding RNAs (lncRNAs) contribute toward regulating gene expression and cell
differentiation and may be involved in the pathogenesis of several diseases. The objective of …