The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Endothelial dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches

DJ Medina-Leyte, O Zepeda-García… - International journal of …, 2021 - mdpi.com
Coronary artery disease (CAD) and its complications are the leading cause of death
worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the …

[HTML][HTML] Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics

AS Bhale, K Venkataraman - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Apolipoprotein A1 (ApoA1) is a member of the Apolipoprotein family of proteins. It's
a vital protein that helps in the production of high-density lipoprotein (HDL) particles, which …

The role of interleukin-6 family members in cardiovascular diseases

Y Feng, D Ye, Z Wang, H Pan, X Lu, M Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …

The vascular endothelium and coagulation: homeostasis, disease, and treatment, with a focus on the von willebrand factor and factors VIII and V

JAD Pablo-Moreno, LJ Serrano, L Revuelta… - International Journal of …, 2022 - mdpi.com
The vascular endothelium has several important functions, including hemostasis. The
homeostasis of hemostasis is based on a fine balance between procoagulant and …

Involvement of fatty acids and their metabolites in the development of inflammation in atherosclerosis

S Kotlyarov, A Kotlyarova - International journal of molecular sciences, 2022 - mdpi.com
Despite all the advances of modern medicine, atherosclerosis continues to be one of the
most important medical and social problems. Atherosclerosis is the cause of several …

Inflammatory mediators of endothelial dysfunction

E Dri, E Lampas, G Lazaros, E Lazarou, P Theofilis… - Life, 2023 - mdpi.com
Endothelial dysfunction (ED) is characterized by imbalanced vasodilation and
vasoconstriction, elevated reactive oxygen species (ROS), and inflammatory factors, as well …

Do interleukin-1 and interleukin-6 antagonists hold any place in the treatment of atherosclerotic cardiovascular disease and related co-morbidities? an overview of …

A Dimosiari, D Patoulias, GD Kitas… - Journal of Clinical …, 2023 - mdpi.com
Cardiovascular disease (CVD) constitutes a real pandemic of the 21st century. According to
data from the Centers for Disease Control and Prevention, one person dies every 34 min …

Therapeutic Role and Potential Mechanism of Resveratrol in Atherosclerosis: TLR4/NF‐κB/HIF‐1α

L Guo, X Zhang, N Lv, L Wang, J Gan… - Mediators of …, 2023 - Wiley Online Library
Atherosclerosis, the main pathological basis of cardiovascular disease, is a chronic
inflammatory disease that severely affects the quality of human life. Resveratrol (Res) is a …

Chronic stress a potential suspect zero of atherosclerosis: a systematic review

L Meng, Y Zhang, Y Luo, T Gong, D Liu - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Atherosclerosis (AS) is a chronic vascular inflammatory disease, in which the lipid
accumulation in the intima of the arteries shows yellow atheromatous appearance, which is …