A holistic review on Cryptococcus neoformans

SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

The status of cryptococcosis in Latin America

C Firacative, J Lizarazo, MT Illnait-Zaragozí… - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …

Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen

FH Santiago-Tirado, MD Onken, JA Cooper, RS Klein… - MBio, 2017 - Am Soc Microbiol
The blood-brain barrier (BBB) protects the central nervous system (CNS) by restricting the
passage of molecules and microorganisms. Despite this barrier, however, the fungal …

Adaptive Immunity to Cryptococcus neoformans Infections

L Mukaremera, K Nielsen - Journal of fungi, 2017 - mdpi.com
The Cryptococcus neoformans/Cryptococcus gattii species complex is a group of fungal
pathogens with different phenotypic and genotypic diversity that cause disease in …

Macrophage Mediated Immunomodulation During Cryptococcus Pulmonary Infection

Y Wang, S Pawar, O Dutta, K Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Macrophages are key cellular components of innate immunity, acting as the first line of
defense against pathogens to modulate homeostatic and inflammatory responses. They …

Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis

S Okurut, DR Boulware, E Okafor, J Rhein… - Frontiers in …, 2023 - frontiersin.org
Introduction Survival among people with HIV-associated cryptococcal meningitis (CM)
remains low, particularly among women, despite the currently optimal use of antifungal …

The immunopathogenesis of cryptococcal immune reconstitution inflammatory syndrome: understanding a conundrum

DB Meya, YC Manabe, DR Boulware… - Current opinion in …, 2016 - journals.lww.com
The immunopathogenesis of cryptococcal immune reconstitution... : Current Opinion in Infectious
Diseases The immunopathogenesis of cryptococcal immune reconstitution inflammatory …

Cryptococcal lung infections

K Skolnik, S Huston, CH Mody - Clinics in Chest Medicine, 2017 - chestmed.theclinics.com
Cryptococcus remains one of the leading causes of acquired immunodeficiency syndrome
(AIDS)-related deaths, and is among the most common fungal pathogens worldwide. 1 …

Variability in innate host immune responses to cryptococcosis

M Garelnabi, RC May - Memórias do Instituto Oswaldo Cruz, 2018 - SciELO Brasil
Cryptococcosis is an invasive fungal disease caused by Cryptococcus neoformans and the
closely related species C. gattii. The severe form of the disease, cryptococcal meningitis …