Chronic myeloid leukemia (CML) is a clonal myeloproliferative expansion of transformed,
primitive hematopoietic progenitor cells. It involves myeloid, monocytic, erythroid …

qRT-PCR (real-time reverse transcription-PCR) has become the benchmark for the detection
and quantification of RNA targets and is being utilized increasingly in novel clinical …

Chronic myelogenous leukemia is a myeloproliferative disorder. It is characterized by a
biphasic or triphasic clinical course in which a benign chronic phase is followed by …

The prognosis of patients with chronic myelogenous leukemia (CML) has significantly
improved over the last 20 years. Whereas the median survival durations were 4-5 years in …

Background The multikinase inhibitor dasatinib exerts growth‐inhibitory effects in patients
with imatinib‐resistant chronic myeloid leukaemia (CML). In first clinical trials, side effects of …

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a
characteristic clinical course in which a chronic phase of variable duration precedes an …

Fluorescence in situ hybridization (FISH) is a powerful technique for detecting DNA or RNA
sequences in cells, tissues and tumors. This molecular cytogenetic technique enables the …

Background Recent data suggest that the mammalian target of rapamycin (mTOR) is
involved in the regulation of growth of neoplastic cells in chronic myeloid leukaemia (CML) …

Background: Current practice guidelines for managing patients with chronic myelogenous
leukemia (CML) call for monitoring BCR-ABL transcript concentrations with a quantitative …

Philadelphia chromosome (Ph)‐positive acute lymphoblastic leukemia (ALL) is diagnosed
rarely in children, but constitutes the most frequent cytogenetic abnormality in adults with …