New therapeutics in endometriosis: a review of hormonal, non-hormonal, and non-coding RNA treatments

G Brichant, I Laraki, L Henry, C Munaut… - International Journal of …, 2021 - mdpi.com
Endometriosis is defined as endometrial-like tissue outside the uterine cavity. It is a chronic
inflammatory estrogen-dependent disease causing pain and infertility in about 10% of …

[HTML][HTML] Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis

HH Shen, T Zhang, HL Yang, ZZ Lai, WJ Zhou, J Mei… - Theranostics, 2021 - ncbi.nlm.nih.gov
Menstruation occurs in few species and involves a cyclic process of proliferation, breakdown
and regeneration under the control of ovarian hormones. Knowledge of normal endometrial …

Polyphenols as a diet therapy concept for endometriosis—current opinion and future perspectives

A Gołąbek, K Kowalska, A Olejnik - Nutrients, 2021 - mdpi.com
Endometriosis represents an often painful, estrogen-dependent gynecological disorder,
defined by the existence of endometrial glands and stroma exterior to the uterine cavity. The …

The role of selected dietary factors in the development and course of endometriosis

A Markowska, M Antoszczak, J Markowska… - Nutrients, 2023 - mdpi.com
Endometriosis is a chronic disease with a complex, heterogeneous pathogenesis that affects
about 10% of women of reproductive age, causing pain and leading to infertility. Treatment …

The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

Omics-based novel strategies in the diagnosis of endometriosis

M Samare-Najaf, SA Razavinasab… - Critical Reviews in …, 2024 - Taylor & Francis
Endometriosis, an enigmatic and chronic disorder, is considered a debilitating condition
despite being benign. Globally, this gynecologic disorder affects up to 10% of females of …

Imperatorin alleviated endometriosis by inhibiting the activation of PI3K/Akt/NF-κB pathway in rats

T Ma, P Liu, J Wei, M Zhao, X Yao, X Luo, S Xu - Life sciences, 2021 - Elsevier
Aims Most therapeutic drugs of endometriosis have been contraceptives but symptoms recur
in up to 75% of cases, which makes it a presses need to try to find novel and safer …

Insight into the Potential Mechanisms of Endocrine Disruption by Dietary Phytoestrogens in the Context of the Etiopathogenesis of Endometriosis

D Szukiewicz - International Journal of Molecular Sciences, 2023 - mdpi.com
Phytoestrogens (PEs) are estrogen-like nonsteroidal compounds derived from plants (eg,
nuts, seeds, fruits, and vegetables) and fungi that are structurally similar to 17β-estradiol …

The combined impact of testosterone and Western-style diet on endometriosis severity and progression in rhesus macaques

CV Bishop, DL Takahashi, F Luo… - Biology of …, 2023 - academic.oup.com
Polycystic ovary syndrome (PCOS) is associated with irregular menstrual cycles,
hyperandrogenemia, and obesity. It is currently accepted that women with PCOS are also at …

[PDF][PDF] Unopposed estrogens: current and future perspectives.

MM Oliva, R Gambioli, G Forte, G Porcaro… - European Review for …, 2022 - researchgate.net
Estrogens and progestogens act on female reproductive tissues in opposite ways. As they
counteract each other actions, the correct balance between these two classes of hormones …