The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

The blood–brain barrier (BBB) plays a vital role in maintaining the specialized
microenvironment of the neural tissue. It separates the peripheral circulatory system from the …

The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

The nature of fluid dynamics within the brain parenchyma is a focus of intensive research. Of
particular relevance is its participation in diseases associated with protein accumulation and …

Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …

Alzheimer's disease (AD) is the most common form of dementia. AD brain pathology starts
decades before the onset of clinical symptoms. One early pathological hallmark is blood …

Objective To determine whether serum neurofilament light (NfL) correlates with CSF NfL,
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …

Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex
of Alzheimer's disease (AD) patients several decades ago. However, their role in AD …