[HTML][HTML] Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer's disease in rats

X Chen, M Zhang, M Ahmed, KM Surapaneni… - Saudi journal of …, 2021 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disease categorized by the
deficiency in the cognition and memory. Approximately 50 million peoples has the AD, which …

Antioxidant supplementation in oxidative stress-related diseases: What have we learned from studies on alpha-tocopherol?

FL Meulmeester, J Luo, LG Martens, K Mills… - Antioxidants, 2022 - mdpi.com
Oxidative stress has been proposed as a key contributor to lifestyle-and age-related
diseases. Because free radicals play an important role in various processes such as …

The KEAP1-NRF2 system in healthy aging and longevity

D Matsumaru, H Motohashi - Antioxidants, 2021 - mdpi.com
Aging is inevitable, but the inherently and genetically programmed aging process is
markedly influenced by environmental factors. All organisms are constantly exposed to …

TXNIP: A Double‐Edged Sword in Disease and Therapeutic Outlook

M Pan, F Zhang, K Qu, C Liu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Thioredoxin‐interacting protein (TXNIP) was originally named vitamin D3 upregulated
protein‐1 (VDUP1) because of its ability to bind to thioredoxin (TRX) and inhibit TRX …

Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Crosstalk between calcium and ROS in pathophysiological conditions

S Feno, G Butera, D Vecellio Reane… - Oxidative medicine …, 2019 - Wiley Online Library
Calcium ions are highly versatile intracellular signals that regulate many cellular processes.
The key to achieving this pleiotropic role is the spatiotemporal control of calcium …

Amelioration of acrylamide induced neurotoxicity by benzo [b] thiophene analogs via glutathione redox dynamics in zebrafish larvae

B Haridevamuthu, T Manjunathan, A Guru… - Brain Research, 2022 - Elsevier
Acrylamide is a thermal process contaminant, which gets global attention due to its
neurotoxic nature and its omnipresence in carbohydrate-rich foods. Chronic exposure to …

Nanoformulations to enhance the bioavailability and physiological functions of polyphenols

B Yang, Y Dong, F Wang, Y Zhang - Molecules, 2020 - mdpi.com
Polyphenols are micronutrients that are widely present in human daily diets. Numerous
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …

Therapeutic landscape for Batten disease: current treatments and future prospects

TB Johnson, JT Cain, KA White… - Nature Reviews …, 2019 - nature.com
Batten disease (also known as neuronal ceroid lipofuscinoses) constitutes a family of
devastating lysosomal storage disorders that collectively represent the most common …

Alzheimer's disease and Parkinson's disease: a nutritional toxicology perspective of the impact of oxidative stress, mitochondrial dysfunction, nutrigenomics and …

A Agnihotri, OI Aruoma - Journal of the American College of …, 2020 - Taylor & Francis
Introduction: Alzheimer's disease is primarily a dementia-related disorder from progressive
cognitive deterioration and memory impairment, while Parkinson's disease is primarily a …