Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition
leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular …

Naturally derived polymeric biomaterials, such as collagens, silks, elastins, alginates, and
fibrins are utilized in tissue engineering due to their biocompatibility, bioactivity, and tunable …

Corneal transplantation remains the ultimate treatment option for advanced stromal and
endothelial disorders. Corneal tissue engineering has gained increasing interest in recent …

Keratin is a kind of natural polymer that is abundant in feathers, wool, and hair. Being one of
the natural biomolecules, keratin has excellent biological activity, biocompatibility …

Amniotic membrane (AM) transplantation is the clinical standard for ocular surface
reconstruction, however recently keratin film (KF) has been proposed as an alternative …

Abstract On March 21, 2015, a meeting was held in London, United Kingdom, to address the
progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting …

Severe ocular surface disorders can result in deficiency of limbal stem cells that is potentially
associated with chronic inflammation, impaired vision and even blindness. Advanced stem …

Limbal stem cell deficiency (LSCD) is a complex blinding disease of the cornea, which
cannot be treated with conventional corneal transplants. Instead, a stem cell (SC) graft is …

Cornea tissue is in high demand by tissue donation centres globally, and thus tissue
engineering cornea, which is the main topic of corneal translational medicine, can serve as …

Corneal integrity is essential for visual function. Transplantation remains the most common
treatment option for advanced corneal diseases. A global donor material shortage requires a …