Advancements in prophylactic and therapeutic nanovaccines

P Bhardwaj, E Bhatia, S Sharma, N Ahamad… - Acta Biomaterialia, 2020 - Elsevier
Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …

Nanovaccine‐based strategies to overcome challenges in the whole vaccination cascade for tumor immunotherapy

L Qin, H Zhang, Y Zhou, CS Umeshappa, H Gao - Small, 2021 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …

Nanoparticles as smart carriers for enhanced cancer immunotherapy

N Thakur, S Thakur, S Chatterjee, J Das… - Frontiers in Chemistry, 2020 - frontiersin.org
Cancer immunotherapy has emerged as a promising strategy for the treatment of many
forms of cancer by stimulating body's own immune system. This therapy not only eradicates …

Supramolecular immunotherapy of cancer based on the self‐assembling peptide design

R Chang, X Yan - Small Structures, 2020 - Wiley Online Library
Supramolecular peptide assemblies with specific motifs have the advantages of high
immunogenicity, regulated immune response, and increased multiple functions in improving …

Tuning mesoporous silica nanoparticles in novel avenues of cancer therapy

S Shah, P Famta, D Bagasariya… - Molecular …, 2022 - ACS Publications
The global menace of cancer has led to an increased death toll in recent years. The constant
evolution of cancer therapeutics with novel delivery systems has paved the way for …

Carrier-free nanovaccine: An innovative strategy for ultrahigh melanoma neoantigen loading

T Zeng, W Zang, H Xiao, Y Jiang, S Lin, M Wang, S Li… - ACS …, 2023 - ACS Publications
In personalized cancer immunotherapy, developing an effective neoantigen nanovaccine
with high immunogenicity is a significant challenge. Traditional nanovaccine delivery …

Peptide-functionalized,-assembled and-loaded nanoparticles in cancer therapy

J Dai, M Ashrafizadeh, AR Aref, G Sethi, YN Ertas - Drug Discovery Today, 2024 - Elsevier
The combination of peptides and nanoparticles in cancer therapy has shown synergistic
results. Nanoparticle functionalization with peptides can increase their targeting ability …

[HTML][HTML] Engineering customized nanovaccines for enhanced cancer immunotherapy

J Guo, C Liu, Z Qi, T Qiu, J Zhang, H Yang - Bioactive Materials, 2024 - Elsevier
Nanovaccines have gathered significant attention for their potential to elicit tumor-specific
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …

CpG-based nanovaccines for cancer immunotherapy

W Chen, M Jiang, W Yu, Z Xu, X Liu, Q Jia… - International Journal …, 2021 - Taylor & Francis
Cancer has been a serious health hazard to the people all over the world with its high
incidence and horrible mortality. In recent years, tumor vaccines in immunotherapy have …

[HTML][HTML] Adjuvant-free peptide vaccine targeting Clec9a on dendritic cells can induce robust antitumor immune response through Syk/IL-21 axis

S Gou, S Wang, W Liu, G Chen, D Zhang, J Du… - Theranostics, 2021 - ncbi.nlm.nih.gov
Dendritic cells (DCs) can process the antigens of cancer vaccine and thus stimulate the
CD8+ T cells to recognize and kill the tumor cells that express these antigens. However, lack …