[HTML][HTML] Role of cytokines in experimental and human visceral leishmaniasis

M Samant, U Sahu, SC Pandey… - Frontiers in cellular and …, 2021 - frontiersin.org
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

[HTML][HTML] Applications of nanomaterials in leishmaniasis: a focus on recent advances and challenges

K Saleem, Z Khursheed, C Hano, I Anjum, S Anjum - Nanomaterials, 2019 - mdpi.com
Leishmaniasis is a widely distributed protozoan vector-born disease affecting almost 350
million people. Initially, chemotherapeutic drugs were employed for leishmania treatment but …

Global genome diversity of the Leishmania donovani complex

SU Franssen, C Durrant, O Stark, B Moser, T Downing… - Elife, 2020 - elifesciences.org
Protozoan parasites of the Leishmania donovani complex–L. donovani and L. infantum–
cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome …

From infection to vaccination: reviewing the global burden, history of vaccine development, and recurring challenges in global leishmaniasis protection

G Volpedo, RH Huston, EA Holcomb… - Expert review of …, 2021 - Taylor & Francis
Introduction Leishmaniasis is a major public health problem and the second most lethal
parasitic disease in the world due to the lack of effective treatments and vaccines. Even …

[HTML][HTML] Antileishmanial drug discovery and development: time to reset the model?

AI Olias-Molero, C de la Fuente, M Cuquerella… - Microorganisms, 2021 - mdpi.com
Leishmaniasis is a vector-borne parasitic disease caused by Leishmania species. The
disease affects humans and animals, particularly dogs, provoking cutaneous …

[HTML][HTML] Revisiting the mechanisms of immune evasion employed by human parasites

M Chulanetra, W Chaicumpa - Frontiers in cellular and infection …, 2021 - frontiersin.org
For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

[HTML][HTML] Immunotherapy and immunochemotherapy in combating visceral leishmaniasis

G Yadagiri, A Singh, K Arora, SL Mudavath - Frontiers in Medicine, 2023 - frontiersin.org
Visceral leishmaniasis (VL), a vector borne disease is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of genus Leishmania. Globally, VL is …

[HTML][HTML] Leishmaniasis in the United States: emerging issues in a region of low endemicity

JM Curtin, NE Aronson - Microorganisms, 2021 - mdpi.com
Leishmaniasis, a chronic and persistent intracellular protozoal infection caused by many
different species within the genus Leishmania, is an unfamiliar disease to most North …

[HTML][HTML] Multifunctional, TNF-α and IFN-γ-Secreting CD4 and CD8 T cells and CD8High T cells are associated with the cure of human visceral leishmaniasis

LS Rodrigues, AS Barreto, LGS Bomfim… - Frontiers in …, 2021 - frontiersin.org
Visceral leishmaniasis (VL) is a chronic and often fatal disease caused by protozoans of the
genus Leishmania that affects millions of people worldwide. Patients with symptomatic VL …

[HTML][HTML] In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani

S Saha, S Vashishtha, B Kundu, M Ghosh - BMC bioinformatics, 2022 - Springer
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …