[HTML][HTML] Leishmania infantum β-Tubulin Identified by Reverse Engineering Technology through Phage Display Applied as Theranostic Marker for Human Visceral …

LE Costa, PT Alves, AP Carneiro, ACS Dias… - International Journal of …, 2019 - mdpi.com
Two Leishmania infantum mimotopes (B10 and C01) identified by phage display showed to
be antigenic and immunogenic for visceral (VL) and tegumentary (TL) leishmaniasis; …

[PDF][PDF] Total serum N-glycans mark visceral leishmaniasis in human infections with Leishmania infantum

GN Porcino, MR Bladergroen, V Dotz, S Nicolardi… - Iscience, 2023 - cell.com
Visceral leishmaniasis (VL) is a clinical form of leishmaniasis with high mortality rates when
not treated. Diagnosis suffers from invasive techniques and sub-optimal sensitivities. The …

A biomarker for tegumentary and visceral leishmaniasis based on a recombinant Leishmania hypothetical protein

DP Lage, AS Machado, FF Ramos, PC Silveira… - Immunobiology, 2019 - Elsevier
The measures for leishmaniasis control include the precise diagnosis of disease. However,
although several recombinant antigens have been tested with this biotechnological purpose …

Antigenicity, immunogenicity and protective efficacy of a conserved Leishmania hypothetical protein against visceral leishmaniasis

DS Dias, VT Martins, PAF Ribeiro, FF Ramos… - Parasitology, 2018 - cambridge.org
In this study, a Leishmania hypothetical protein, LiHyS, was evaluated regarding its
antigenicity, immunogenicity and protective efficacy against visceral leishmaniasis (VL) …

Immunotherapeutic potential of Leishmania (Leishmania) donovani Th1 stimulatory proteins against experimental visceral leishmaniasis

NK Yadav, S Joshi, S Ratnapriya, AA Sahasrabuddhe… - Vaccine, 2018 - Elsevier
An effective therapeutic vaccination strategy is required for controlling visceral leishmaniasis
(VL), a fatal systemic disease, through boosting the immunosuppressed state in Leishmania …

Repurposing approved protein kinase inhibitors as potent anti-leishmanials targeting Leishmania MAP kinases

A Bhattacharjee, A Bagchi, S Sarkar, S Bawali… - Life Sciences, 2024 - Elsevier
Aims Leishmaniasis, caused by the protozoan parasite poses a significant health burden
globally. With a very few specific drugs, increased drug resistance it is important to look for …

A Non‐pathogenic Recombinant Leishmania Expressing Lipophosphoglycan 3 Against Experimental Infection with Leishmania infantum

L Pirdel, S Farajnia - Scandinavian journal of immunology, 2017 - Wiley Online Library
Visceral leishmaniasis (VL) is caused by Leishmania infantum in the Mediterranean basin
and affects primarily children and immunosuppressed individuals. Various strategies of …

[HTML][HTML] Investigation of the antigenicity and protective efficacy of Leishmania promastigote membrane antigens in search of potential diagnostic and vaccine …

SA Ejazi, S Ghosh, A Bhattacharyya, M Kamran… - Parasites & …, 2020 - Springer
Background Visceral leishmaniasis (VL), is a parasitic disease that causes serious medical
consequences if treatment is delayed. Despite a decline in the number of VL cases in the …

Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis

J Zhang, J He, X Liao, Y Xiao, C Liang, Q Zhou… - Immunobiology, 2021 - Elsevier
The most dangerous form of leishmaniasis is Visceral leishmaniasis (VL). The elimination of
VL depends not only on agent treatments but also on effective vaccines against Leishmania …

Uptake pathways of cell-penetrating peptides in the context of drug delivery, gene therapy, and vaccine development

M Dowaidar - Cellular Signalling, 2024 - Elsevier
Cell-penetrating peptides have been extensively utilized for the purpose of facilitating the
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …