Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

The etiology of preeclampsia

E Jung, R Romero, L Yeo, N Gomez-Lopez… - American journal of …, 2022 - Elsevier
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …

Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study

P Li, H Wang, L Guo, X Gou, G Chen, D Lin, D Fan… - BMC medicine, 2022 - Springer
Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …

SARS-CoV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis

A Conde-Agudelo, R Romero - American journal of obstetrics and …, 2022 - Elsevier
Objective To examine the relationship between SARS-CoV-2 infection during pregnancy
and the risk for preeclampsia. Data Sources MEDLINE, Embase, POPLINE, CINAHL …

Preeclampsia and COVID-19: results from the INTERCOVID prospective longitudinal study

AT Papageorghiou, P Deruelle, RB Gunier… - American journal of …, 2021 - Elsevier
Background It is unclear whether the suggested link between COVID-19 during pregnancy
and preeclampsia is an independent association or if these are caused by common risk …

Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …

A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia

MM Costantine, H West, KL Wisner, S Caritis… - American journal of …, 2021 - Elsevier
Background Preeclampsia remains a major cause of maternal and neonatal morbidity and
mortality. Biologic plausibility, compelling preliminary data, and a pilot clinical trial support …

Hypoxia and mitochondrial dysfunction in pregnancy complications

XQ Hu, L Zhang - Antioxidants, 2021 - mdpi.com
Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …

[HTML][HTML] Malaria in pregnancy: from placental infection to its abnormal development and damage

CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …