Living on the edge of the CNS: meninges cell diversity in health and disease

J Derk, HE Jones, C Como, B Pawlikowski… - Frontiers in cellular …, 2021 - frontiersin.org
The meninges are the fibrous covering of the central nervous system (CNS) which contain
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …

The clinical manifestations, molecular mechanisms and treatment of craniosynostosis

E Stanton, M Urata, JF Chen… - Disease Models & …, 2022 - journals.biologists.com
Craniosynostosis is a major congenital craniofacial disorder characterized by the premature
fusion of cranial suture (s). Patients with severe craniosynostosis often have impairments in …

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

A Cugurra, T Mamuladze, J Rustenhoven, T Dykstra… - Science, 2021 - science.org
INTRODUCTION Myeloid cells are highly heterogeneous, with distinct ontogenies and
immune functions. The diverse role of myeloid populations, including monocytes …

A multi-stem cell basis for craniosynostosis and calvarial mineralization

S Bok, AR Yallowitz, J Sun, J McCormick, M Cung… - Nature, 2023 - nature.com
Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of
the calvarial stem cells (CSCs) that produce fusion-driving osteoblasts in craniosynostosis …

DLP printed hDPSC-loaded GelMA microsphere regenerates dental pulp and repairs spinal cord

Y Qian, J Gong, K Lu, Y Hong, Z Zhu, J Zhang, Y Zou… - Biomaterials, 2023 - Elsevier
Dental pulp regeneration is ideal for irreversible pulp or periapical lesions, and in situ stem
cell therapy is one of the most effective therapies for pulp regeneration. In this study, we …

Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate

WB Swanson, M Omi, Z Zhang, HK Nam, Y Jung… - Biomaterials, 2021 - Elsevier
Craniosynostosis is a debilitating birth defect characterized by the premature fusion of
cranial bones resulting from premature loss of stem cells located in suture tissue between …

Digital light processing (DLP) in tissue engineering: From promise to reality, and perspectives

J Gong, Y Qian, K Lu, Z Zhu, L Siow, C Zhang… - Biomedical …, 2022 - iopscience.iop.org
Tissue engineering technology provides a revolutionary strategy to completely restore the
structure and function of damaged tissues or organs. Digital light processing (DLP), as a …

Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies

Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …

Biomimetic design of double-sided functionalized silver nanoparticle/bacterial cellulose/hydroxyapatite hydrogel mesh for temporary cranioplasty

X Yang, J Huang, C Chen, L Zhou… - ACS Applied Materials …, 2023 - ACS Publications
A structurally stable and antibacterial biomaterial used for temporary cranioplasty with
guided bone regeneration (GBR) effects is an urgent clinical requirement. Herein, we …

Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis

L Ma, Q Chang, F Pei, M Liu, W Zhang, YK Hong… - Cell Stem Cell, 2023 - cell.com
The meninges lie in the interface between the skull and brain, harboring lymphatic
vasculature and skull progenitor cells (SPCs). How the skull and brain communicate …