[HTML][HTML] The Pathological Mechanisms of Hearing Loss Caused by KCNQ1 and KCNQ4 Variants

K Homma - Biomedicines, 2022 - mdpi.com
Deafness-associated genes KCNQ1 (also associated with heart diseases) and KCNQ4 (only
associated with hearing loss) encode the homotetrameric voltage-gated potassium ion …

[HTML][HTML] Behavior of KCNQ Channels in Neural Plasticity and Motor Disorders

SP Singh, M William, M Malavia, XP Chu - Membranes, 2022 - mdpi.com
The broad distribution of voltage-gated potassium channels (VGKCs) in the human body
makes them a critical component for the study of physiological and pathological function …

Natural History of KCNQ4 p.G285S Related Hearing Loss, Construction of iPSC and Mouse Model

X Zhang, T Shi, J Li, X Wu, K Wu, D Li… - The …, 2024 - Wiley Online Library
Objective KCNQ4 is one of the most common disease‐causing genes involved in autosomal
dominant non‐syndromic hearing loss. We previously found that patients with KCNQ4 p …

The frequency dependence of prestin-mediated fast electromotility for mammalian cochlear amplification

S Takahashi, Y Zhou, MA Cheatham, K Homma - bioRxiv, 2024 - biorxiv.org
Prestin, s voltage-driven motor activity confers sound-elicited somatic electromotility in
auditory outer hair cells (OHCs) and is essential for the exquisite sensitivity and frequency …

Inhibition of Kv7/M Channel Currents by Fangchinoline

H Li, DD Geng, R Zheng, R Wang, Y Li, Y Liu, Q Jia… - Pharmacology, 2023 - karger.com
Abstract Introduction: Voltage-gated Kv7/M potassium channels play an essential role in the
control of membrane potential and neuronal excitability. Fangchinoline, a …

[HTML][HTML] A Short Overview on Hearing Loss and Related Auditory Defects

H Khan, H Idrees, Z Munir… - Auditory System-Function …, 2022 - intechopen.com
Hearing is the ability of a person to recognize sound in the surroundings and it makes
communication possible. Ear is the human organ serving as a transducer that perceives …

Rol de los canales Kv7. 4 en la sordera de progresión lenta DFNA2

C Carignano - 2022 - repositoriodigital.uns.edu.ar
La recirculación del potasio (K+) es un proceso indispensable para la audición, que tiene
lugar en el órgano de Corti (OC). Ante la presencia de estímulos sonoros, el K+ ingresa a …

[引用][C] A Short Overview on Hearing Loss and Related Auditory Defects

H Khan, H Idrees, Z Munir, M Ramzan