Cutaneous T cell lymphoma (CTCL) is a spectrum of lymphoproliferative disorders caused
by the infiltration of malignant T cells into the skin. The most common variants of CTCL …

Deregulation of STAT signaling has been implicated in the pathogenesis for a variety of
cancers, including CTCL. Recent reports indicate that loss of STAT4 expression is an …

Inappropriately regulated expression of interleukin (IL)-17A is associated with the
development of inflammatory diseases and cancer. However, little is known about the role of …

Biopsies from patients with cutaneous T-cell lymphoma (CTCL) exhibit stage-dependent
increase in angiogenesis. However, the molecular mechanisms responsible for the …

HTLV-1 is estimated to affect~ 20 million people worldwide and in~ 5% of carriers it
produces Adult T-Cell Leukemia/Lymphoma (ATLL), which can often masquerade and …

Cutaneous T-cell lymphoma (CTCL) is a potentially devastating malignancy. The
pathogenesis of this cancer remains poorly elucidated. Previous studies focused on analysis …

Purpose: The pathogenesis of cutaneous T-cell lymphoma (CTCL) remains only partially
understood. A number of recent studies attempted to identify novel diagnostic markers and …

B-lymphoid kinase (Blk) is exclusively expressed in B cells and thymocytes. Interestingly,
transgenic expression of a constitutively active form of Blk in the T-cell lineage of mice …

Cytokines are considered to be of major importance for the pathogenesis of cutaneous T‐
cell lymphomas (CTCL). Their impact may result from autocrine, paracrine or endocrine …

Using a cDNA microarray, we compared the expression of approximately 8000 genes
between two unique, clonally related T cell lines derived from different stages of a …